Xerova 10 mg (Tablet)
Unit Price: ৳ 12.00 (4 x 7: ৳ 336.00)
Strip Price: ৳ 84.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Title
- Xerova 10 mg Tablet
Categories
- Medicine
- Pharmaceutical
Description
- Selective inhibitor of HMG-CoA reductase
- Reduces elevated cholesterol levels
- Lowers triglycerides
- Adjunct to diet for reducing total cholesterol and LDL cholesterol
DosageAndAdministration
- Oral administration
- Recommended starting dose of 10 or 20 mg once daily
- Dose adjustment based on lipid levels analysis
- Usual max dose of 80 mg once daily
TherapeuticClass
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Indications
- Reduction of total cholesterol and LDL cholesterol
- Treatment of hypertriglyceridemia and dyslipidemia
- Prevention of cardiovascular events
ModeOfAction
- Selective inhibitor of HMG-CoA reductase
- Lowers plasma cholesterol and lipoprotein levels
- Increases hepatic LDL receptors for enhanced uptake of LDL
Absorption
- Rapid absorption after oral administration
- Maximum plasma concentrations occur within 1 to 2 hours
Distribution
- Mean volume of distribution of approximately 381 liters
- 98% bound to plasma proteins
Metabolism
- Extensively metabolized to ortho- and parahydroxylated derivatives and beta-oxidation products
- Importance of metabolism by cytochrome P450 3A4
Excretion
- Eliminated primarily in bile following hepatic and/or extra-hepatic metabolism
- Mean plasma elimination half-life of approximately 14 hours
Interaction
- Concurrent administration with cyclosporine, fibric acid derivatives, or erythromycin increases risk of myopathy
- Altered plasma concentrations with coadministration of antacid
- Increased digoxin concentrations with coadministration of atorvastatin
- Coadministration with oral contraceptives may increase AUC values for certain hormones
Contraindications
- Hypersensitivity to any component of the medication
- Active liver disease
- Unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
SideEffects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Headache
- Rash
- Asthenia
- Myalgia
PregnancyAndLactation
- Contraindicated during pregnancy
- Not recommended during breastfeeding
- Potential for serious adverse reactions in infants
PrecautionsAndWarnings
- Liver function tests should be performed before initiation and periodically thereafter
- Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected
SpecialPopulations
- Plasma concentrations are higher in healthy elderly subjects
- No influence on plasma concentrations or LDL-C reduction in renal disease
- Markedly increased plasma concentrations in chronic alcoholic liver disease
OverdoseEffects
- Specific treatment not available
- Symptomatic treatment and supportive measures instituted
StorageConditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
ChemicalStructure
- Molecular formula: C33H35FN2O5
- Chemical structure available
CommonQuestions
- What is Xerova 10 mg Tablet?
- How to take Xerova 10 mg Tablet?
- Uses of Xerova 10 mg Tablet
- Side effects of Xerova 10 mg Tablet
- Storage and disposal instructions
- Can increase risk of diabetes
- Safe for long-term use
- Does not cause weight loss
- Can make you tired
- Not a blood thinner
QuickTips
- Safe medication, may cause diarrhea, gas, or upset stomach
- Inform doctor if experience fatigue, muscle weakness, or liver problems
- Monitor liver function, blood sugar level if diabetic
- Avoid if pregnant, planning pregnancy, or breastfeeding