Clovate 0.05% (Cream)
10 gm tube: ৳ 58.17
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobetasol propionate |
| Company | Aci limited |
| Also available as |
Indications
- Psoriasis
- Recalcitrant dermatoses
- Lichen planus
- Discoid lupus erythematosus
- Other skin conditions
Composition
- Clobetasol Propionate Cream
- Clobetasol Propionate Ointment
- Clobetasol Propionate Scalp Application
- Clobetasol Propionate Shampoo
- Clobetasol Propionate Lotion
- Clobetasol Propionate Spray
Pharmacology
- Anti-inflammatory
- Antipruritic
- Vasoconstrictive
- Inhibition of allergic reactions
- Reduction of mast cell density
- Inhibition of eosinophil activation
- Cytokine production reduction
- Arachidonic acid metabolism inhibition
Dosage
- Twice daily application
- Thin layer application
- Gentle and complete rubbing
- Short courses for exacerbations
- Occlusion for hyperkeratosis
- Limited treatment duration for children
Administration
- Cutaneous administration
- Creams for moist or weeping surfaces
- Ointments for dry, lichenified or scaly lesions
Interaction
- Inhibition of CYP3A4 metabolism by co-administered drugs
Contraindications
- Rosacea
- Acne vulgaris
- Perioral dermatitis
- Primary cutaneous viral infections
- Hypersensitivity
- Fungal or bacterial infection related skin conditions
- Dermatoses in children under one year of age
Side Effects
- Hypercorticism features from prolonged use
- Local atrophic changes
- Pustular form of psoriasis
- Pigmentation changes
- Exacerbation of symptoms
Pregnancy & Lactation
- Limited data in pregnant women
- Abnormalities in fetal development
- Caution during lactation
Precautions & Warnings
- Avoid long-term continuous therapy particularly in infants and children
- Atrophic changes in the face after prolonged treatment
- Potential hazards in psoriasis treatment
- Care needed for application to eye lids
- Appropriate use of anti-microbial therapy
Use in Special Populations
- Adrenal suppression in infants and children
- Susceptibility of children to atrophic changes
Overdose Effects
- Acute overdosage is unlikely
- Features of hypercortisolism in chronic over-dosage
Therapeutic Class
- Other Topical corticosteroids
Storage Conditions
- Below 30°C temperature
- Protected from light and moisture
- Do not freeze
- Keep out of the reach of children