Dermacort 0.05% (Cream)
10 gm tube: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobetasol propionate |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Psoriasis (excluding widespread plaque psoriasis)
- Recalcitrant dermatoses
- Lichen planus
- Discoid lupus erythematosus
- Other skin conditions
- Adults
- Elderly
- Children over 1 year
Composition
- Clobetasol Propionate Cream: Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Ointment: Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Scalp Application: Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Shampoo: Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Lotion: Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Spray: Clobetasol Propionate BP 0.5 mg (0.05% w/w)
Pharmacology
- Anti-inflammatory
- Antipruritic
- Vasoconstrictive
- Inhibits late phase allergic reactions
- Decreases mast cells density
- Inhibits cytokine production
Dosage
- Cream, Ointment
- Spray
- Shampoo
- Scalp Solution
- Application twice daily
- Limited to 2 consecutive weeks
Administration
- Cutaneous route
- Creams for moist or weeping surfaces
- Ointments for dry, lichenified, or scaly lesions
Interaction
- Inhibition of CYP3A4 metabolism by co-administered drugs
Contraindications
- Rosacea
- Acne vulgaris
- Hypersensitivity
- Viral infections
- Bacterial infections
- Children under one year of age
Side Effects
- Hypercorticism from systemic absorption
- Skin atrophic changes
- Pustular psoriasis
- Hypertrichosis
- Hypersensitivity reactions
Pregnancy & Lactation
- Limited data in pregnant women
- Caution during lactation
Precautions & Warnings
- Avoid long-term continuous therapy
- Atrophic changes on the face
- Avoid ocular exposure
- Hazardous in psoriasis
- Appropriate anti-microbial therapy
Use in Special Populations
- Avoid long-term therapy in children under 12 years
- Adrenal suppression risk in children
Overdose Effects
- Acute overdosage unlikely
- Features of hypercortisolism in chronic overdose
Therapeutic Class
- Other Topical corticosteroids
Storage Conditions
- Keep below 30°C
- Protected from light and moisture
- Do not freeze