Dermasol-S 0.05% (Scalp Solution)
25 ml bottle: ৳ 200.61
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobetasol propionate |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Psoriasis (excluding widespread plaque psoriasis)
- Recalcitrant dermatoses
- Lichen planus
- Discoid lupus erythematosus
- Other skin conditions which do not respond satisfactorily to less potent steroids
Composition
- Clobetasol Propionate Cream: 0.05% w/w
- Clobetasol Propionate Ointment: 0.05% w/w
- Clobetasol Propionate Scalp Application: 0.05% w/w
- Clobetasol Propionate Shampoo: 0.05% w/w
- Clobetasol Propionate Lotion: 0.05% w/w
- Clobetasol Propionate Spray: 0.05% w/w
Pharmacology
Very potent topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties.
Dosage
- Super-high potency topical corticosteroids
- Cream and ointment: Apply twice daily, limited to 2 consecutive weeks
- Spray: Apply once or twice daily, not exceed 50 ml weekly
- Shampoo: Applied once a day to affected areas, limited to 4 consecutive weeks
- Scalp solution: Apply once or twice daily, not exceed 50 ml weekly
Route of Administration
Cutaneous
Interaction
Co-administered drugs that inhibit CYP3A4 can increase systemic exposure.
Contraindications
- Rosacea, acne vulgaris, and perioral dermatitis
- Hypersensitivity to the preparation
- Dermatoses in children under one year of age
Side Effects
- Prolonged use can result in systemic absorption
- Local atrophic changes in the skin
- Pustular form of psoriasis
- Pigmentation changes and hypertrichosis
Pregnancy & Lactation
Limited data in pregnant women, caution in nursing women
Precautions & Warnings
- Avoid long-term continuous therapy, particularly in infants and children
- Atrophic changes on the face
- Care needed to ensure preparation does not enter the eye
- Hazardous in psoriasis for a number of reasons
Use in Special Populations
Long-term continuous therapy should be avoided in infants and children
Overdose Effects
Acute overdosage is unlikely, features of hypercortisolism may occur with chronic over-dosage
Therapeutic Class
Other Topical corticosteroids
Storage Conditions
Keep below 30°C, protected from light and moisture, do not freeze