Nyclobate 0.05% (Scalp Solution)
30 ml bottle: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobetasol propionate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Psoriasis (excluding widespread plaque psoriasis)
- Recalcitrant dermatoses
- Lichen planus
- Discoid lupus erythematosus
- Other skin conditions which do not respond satisfactorily to less potent steroids
Composition
- Clobetasol Propionate Cream: 0.05% w/w
- Clobetasol Propionate Ointment: 0.05% w/w
- Clobetasol Propionate Scalp Application: 0.05% w/w
- Clobetasol Propionate Shampoo: 0.05% w/w
- Clobetasol Propionate Lotion: 0.05% w/w
- Clobetasol Propionate Spray: 0.05% w/w
Pharmacology
Anti-inflammatory, antipruritic and vasoconstrictive properties
Dosage
- Apply a thin layer of Clobetasol Propionate Cream or Ointment to the affected skin areas twice daily
- Maximum weekly dose should not exceed 50 gm/week
- Treatment should be limited to 2 consecutive weeks for super-high potency topical corticosteroids
Administration
Cutaneous. Creams are especially appropriate for moist or weeping surfaces. Ointments are especially appropriate for dry, lichenified or scaly lesions.
Interaction
Co-administered drugs that can inhibit CYP3A4 have been shown to inhibit the metabolism of corticosteroids
Contraindications
- Rosacea, acne vulgaris and perioral dermatitis
- Hypersensitivity to the preparation
- Not indicated in the treatment of primarily infected skin lesions caused by infection with fungi or bacteria
- Dermatoses in children under one year of age
Side Effects
- Prolonged use of large amounts can result in sufficient systemic absorption to produce hypercorticism
- Prolonged and intensive treatment may cause local atrophic changes in the skin
- Exacerbation of symptoms may occur
Pregnancy & Lactation
Limited data in pregnant women. Caution should be exercised when administered to a nursing woman.
Precautions & Warnings
- Long-term continuous topical therapy should be avoided, particularly in infants and children
- Atrophic changes may occur on the face after prolonged treatment with potent topical corticosteroids
- Appropriate anti-microbial therapy should be used whenever treating inflammatory lesions which have become infected
Use in Special Populations
Long-term continuous topical corticosteroid therapy should be avoided in infants and children under 12 years of age
Overdose Effects
Acute overdosage is very unlikely to occur
Therapeutic Class
Other Topical corticosteroids
Storage Conditions
Keep below 30°C temperature, protected from light and moisture. Do not freeze.