Aclobet-N (0.5 mg+5 mg+1 Lac IU)/gm (Cream)

30 gm tube: ৳ 150.00

Medicine Details

Category	Details
Generic	Clobetasol propionate neomycin sulphate nystatin
Company	Acme laboratories ltd
Also available as	Aclobet n 05 mg ointment

Short courses treatment of recalcitrant eczemas
Neurodermatoses
Psoriasis (excluding widespread plaque psoriasis) where secondary bacterial infection or fungal infection is present, suspected or likely to occur
Other inflammatory conditions which do not respond satisfactorily to less active steroids

Apply sparingly to the affected area once or twice daily until improvement occurs
In very resistant lesion, especially where there is hyperkeratosis, the anti-inflammatory effect of this preparation can be enhanced (if necessary) by occluding the treatment area with polythene
Treatment should not be continued for more than 7 days without medical supervision
If a longer course is necessary, it is recommended that treatment should not be continued for more than 4 weeks without the patient's condition being reviewed

Neomycin Sulphate can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents following significant systemic absorption
No hazardous interactions have been reported with use of Clobetasol Propionate or Nystatin

Prolonged use of large amount or treatment of extensive areas can result in sufficient systemic absorption to produce the features of hypercortisolism
Prolonged and intensive treatment with highly active corticosteroid preparations may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels
Reports of pigmentation changes and hypertrichosis with topical steroids

Neomycin present in the maternal blood can cross the placenta and may give rise to a theoretical risk of foetal toxicity
The safety of Clobetasol Propionate has not been established in lactating mothers

Long-term continuous topical therapy should be avoided where possible, particularly in infants and children, as adrenal suppression can occur readily even without occlusion
If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye, as glaucoma might result

Acute overdosage is very unlikely to occur
In the case of chronic overdosage or misuse, the features of hypercortisolism may appear and in this situation, topical steroids should be discontinued gradually