Exovate N (0.5 mg+5 mg+1 Lac IU)/gm (Cream)

25 gm tube: ৳ 90.00

Medicine Details

Category	Details
Generic	Clobetasol propionate neomycin sulphate nystatin
Company	Beximco pharmaceuticals ltd
Also available as	Exovate n 05 mg ointment

Indications

Treatment of recalcitrant eczemas
Neurodermatoses
Psoriasis with secondary bacterial or fungal infection
Treatment of other inflammatory conditions

Pharmacology

Clobetasol Propionate as potent corticosteroid
Neomycin Sulphate as antibiotic
Nystatin as antifungal
Mechanism of action of topical steroids like Clobetasol

Dosage & Administration

Adult dosage and application instructions
Elderly suitability and caution
Children usage and absorption caution

Interaction

Neomycin Sulphate interactions with neuromuscular blocking agents
Expected minimal systemic exposure to Neomycin Sulphate
No hazardous interactions with Clobetasol Propionate or Nystatin

Contraindications

Contraindications for rosacea, acne vulgaris, and perioral dermatitis
Contraindications for primary cutaneous viral infections
Contraindications for hypersensitivity to the preparation

Side Effects

Risk of systemic absorption with prolonged use of large amounts
Local atrophic changes with prolonged use of highly active corticosteroid preparations
Reports of pigmentation changes and hypertrichosis with topical steroids

Pregnancy & Lactation

Theoretical risk of foetal toxicity with topically applied Neomycin
Lack of established safety for Clobetasol Propionate in lactating mothers

Precautions & Warnings

Avoid long-term continuous therapy, especially in infants and children
Care needed when applying to eyelids to prevent entry into the eye
Wash affected eyes thoroughly if medication enters the eye

Overdose Effects

Unlikelihood of acute overdosage
Discontinuation instructions in case of features of hypercortisolism

Therapeutic Class

Clobetasol / Clobetasone & Combined Preparations

Storage Conditions

Recommended storage conditions

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