Relaxton 25 mg/2.5 ml (IV Injection)
2.5 ml ampoule: ৳ 100.00 (1 x 5: ৳ 500.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atracurium besilate |
| Company | Techno drugs ltd |
Indications
- Endotracheal intubation
- Facilitate mechanical ventilation in intensive care
- Muscle relaxant in general anaesthesia
Pharmacology
- Atracurium antagonizes acetylcholine
- Binds competitively with cholinergic receptor sites
- Neuromuscular block reversed by acetylcholinesterase inhibitors
Dosage & Administration
- Initial dose of 300-600 mcg/kg IV
- Subsequent doses of 100-200 mcg/kg IV every 15-25 min
- Infusion rate of 5-10 mcg/kg/min in prolonged procedures
Interaction
- Enhanced neuromuscular blocking effect with general anaesthetics
- Interacts with certain antibiotics, lithium, magnesium salts, procainamide, quinidine
Contraindications
- Hypersensitivity to atracurium, cisatracurium, or benzenesulfonic acid
- Paralysis of respiratory muscles and skeletal muscles
Side Effects
- Skin flush
- Erythema
- Pruritus
- Urticaria
- Wheezing
- Bronchospasm
- Angioedema
- Bradycardia
- Anaphylaxis
Pregnancy & Lactation
- Pregnancy Category C
- Potentially teratogenic effects
- Use only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Patients with cardiovascular disease
- Burn injury
- Asthma
- Conditions that may antagonize neuromuscular blockade
- Conditions that may potentiate neuromuscular blockade
Overdose Effects
- Stimulation of histamine release
- CV effects especially hypotension
Therapeutic Class
- Non depolarizing muscle relaxants
Storage Conditions
- Store between 2-8°C
- Do not freeze