Gento-HC 0.3%+1% (Cream)

10 gm tube: ৳ 60.18

Medicine Details

Indications

  • Treatment of chronic suppurative otitis media
  • Treatment of otitis externa
  • Prophylactic treatment of otitis externa following trauma
  • Treatment of redness, itching, and swelling of the skin

Pharmacology

  • Gentamicin binds to 30s and 50s ribosomal subunits disrupting protein synthesis
  • Hydrocortisone used for anti-inflammatory and immunosuppressive effects

Dosage

  • 2-4 drops in the affected ear three to four times a day
  • For redness, itching, and swelling of the skin: Apply two or three times per day

Administration

  • Ear Drops need to be shaken well immediately before use

Interaction

  • Gentamicin: Additive effect with other neurotoxic and/or nephrotoxic drugs
  • Hydrocortisone: Thiazides may enhance hyperglycaemia and hypokalaemia caused by corticosteroids

Contraindications

  • History of hypersensitivity to aminoglycoside
  • Pregnancy
  • Hepatic impairment

Side Effects

  • Allergic contact dermatitis
  • Transient irritation
  • Increased redness
  • Lacrimation

Pregnancy & Lactation

  • Pregnancy Category- C
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks

Precautions & Warnings

  • Concurrent use of neuromuscular blocking agents
  • Conditions predisposing to ototoxicity and nephrotoxicity
  • Monitor auditory and renal functions

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

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