Avison 1%+0.1% (Cream)

Indications

• Eczematous Mycoses
• Psoriasis
• Tinea Pedis (Athlete’s foot)
• Tinea Corporis (Ring worm)
• Tinea Cruris (Jock itch)
• Inflammatory Intertrigo
• Diaper Dermatitis
• Onychomycoses

Broad Spectrum

1

Antimycotic

1

Anti-inflammatory

1

Anti-pruritic

1

Anti-allergic

1

Active Ingredients

• Econazole Nitrate
• Triamcinolone Acetonide

Range of Action

• Dermatophytes
• Yeasts
• Moulds
• Fungi
• Malassezia furfur
• Nocardia minutissima
• Gram-positive cocci
• Gram-positive bacilli

Antibacterial Effect

1

Gram-positive

1

Dermatomycoses

1

Skin Absorption

Minimal

Systemic Absorption

Increased in damaged skin

Dosage

• Adults: Apply sparingly no more than 2 times daily
• Pediatric Use: Greater susceptibility to side effects

Interaction

• Econazole: Metabolized by CYP3A4/2C9
• Triamcinolone:
  • Lowers plasma salicylates levels
  • Increases risk of GI bleeding and ulceration with NSAIDs
  • Antagonizes blood glucose-lowering effects of antidiabetics
  • Increases risk of hyperkalemia with certain medications

Contraindications

• Hypersensitivity to any ingredients
• Specific skin conditions (tuberculous, varicella, herpes simplex, etc.)

Side Effects

• Transient local irritation
• Adrenal suppression with long-term use
• Infant susceptibility

Pregnancy & Lactation

• Pregnancy: Crosses placenta, avoid prolonged use
• Lactation: Excreted in small amounts in breast milk

Precautions & Warnings

• For external use only
• Discontinue use if hypersensitivity or chemical irritation occurs
• Associated with systemic effects including adrenal suppression
• Skin thinning and atrophy
• Increased risk of superinfection
• Visual disturbance associated with corticosteroid use

Overdose Effects

Treat symptomatically

Therapeutic Class

Triamcinolone & Combined preparations

Storage Conditions

Cool and dry place, away from light

Related Brands

• Aristocort Plus 1%+0.1% (Cream) - aristopharma-ltd