Peviderm 1%+0.1% (Cream)

10 gm tube: ৳ 45.00

Medicine Details

Category	Details
Generic	Econazole nitrate triamcinolone acetonide
Company	Pharmasia limited

Indications

Eczematous Mycoses
Psoriasis
Tinea Pedis (Athlete’s foot)
Tinea Corporis (Ring worm)
Tinea Cruris (Jock itch)
Inflammatory Intertrigo
Diaper Dermatitis
Onychomycoses

Broad Spectrum

This cream is a broad spectrum antimycotic with anti-inflammatory, anti-pruritic and anti-allergic effects.

Active Ingredients

Econazole Nitrate
Triamcinolone Acetonide

Range of Action

Dermatophytes
Yeast
Moulds
Fungi
Malassezia furfur
Nocardia minutissima

Antibacterial Effect

It has antibacterial effect on gram-positive cocci and bacilli.

Pharmacological Properties

Econazole Nitrate is only slightly (<0.1%) absorbed from the skin, and Triamcinolone Acetonide is well absorbed from sites of local application.

Dosage & Administration

This cream should be applied sparingly to the skin lesion no more than 2 times daily, and should not be applied with an occlusive dressing or to large areas of skin on the body.

Pediatric Use

Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome.

Interactions

Econazole is metabolized by CYP3A4/2C9
Triamcinolone may interact with oral anticoagulants, NSAIDs, antidiabetics, amphotericin B, beta-blockers, potassium-depleting diuretics, theophylline, ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin.

Contraindications

Hypersensitivity to any of its ingredients
Specific skin conditions such as tuberculous, varicella, herpes simplex or other viral infections of the skin, or fresh vaccination sites
Decubitus ulcers, viral, bacterial or fungal skin infections, rosacea and rosacea-like dermatitis

Side Effects

Transient local mild irritation
Adrenal suppression on long term continuous topical steroid therapy
An infant's napkin may act as an occlusive dressing.

Pregnancy & Lactation

Topical administration of corticosteroids during pregnancy can cause abnormalities of foetal development
Negligible amount of econazole and to some extent Triamcinolone may be excreted in small amounts in breast milk.

Precautions & Warnings

For external use only
Corticosteroids applied to the skin can be absorbed in sufficient amounts to produce systemic effects
Increased caution is required when treating children
Visual disturbance may be associated with systemic and topical corticosteroid use

Overdose Effects

Corticosteroids applied to the skin, including triamcinolone, can be absorbed in sufficient amounts to produce systemic effects.