Ivanor 7.5 mg (Tablet)
Unit Price: ৳ 35.11 (1 x 10: ৳ 351.10)
Strip Price: ৳ 351.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Ivabradine |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Symptomatic treatment of chronic stable angina pectoris
- Treatment for coronary artery disease patients with normal sinus rhythm
- Alternative for patients unable to tolerate beta-blockers
- Combination therapy with beta-blockers for inadequately controlled patients
Pharmacology
- Pure heart rate lowering agent
- Selective inhibition of the cardiac pacemaker I f current
- Regulation of spontaneous diastolic depolarization in the sinus node
- Decrease in cardiac workload and oxygen consumption
- Prolongation of diastole for increased perfusion of coronary arteries
Dosage & Administration
- Usual starting dose of 5mg twice daily
- May be increased to 7.5mg twice daily based on therapeutic response
- Dosage adjustment if heart rate decreases persistently below 50 bpm
- Lower starting dose for elderly patients
- No dose adjustment required in renal insufficiency patients
Interaction
- Avoid concomitant use with QT wave prolonging medicinal products
- Close cardiac monitoring if combination is necessary
Contraindications
- Hypersensitivity to Ivabradine or any excipients
- Resting heart rate below 60 bpm
- Cardiogenic shock, acute myocardial infarction, severe hypotension
- Severe hepatic insufficiency, sick sinus syndrome, sino-atrial block
- Heart failure, pacemaker dependency, unstable angina
- 3rd degree AV block, combination with strong cytochrome P-450 3A4 inhibitors
Side Effects
- Visual symptoms, blurred vision, bradycardia
- 1st degree AV block, ventricular extrasystoles, headaches, dizziness
Pregnancy & Lactation
- Contraindicated during pregnancy
- Excreted in milk, contraindicated during breast-feeding
Precautions & Warnings
- Mild to moderate hypotension, atrial fibrillation
- Patients with congenital QT syndrome or treated with QT wave prolonging medicinal products
- Moderate hepatic insufficiency, severe renal insufficiency
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
Storage Conditions
- Store below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children