Clindacin Plus 1.2%+0.025% (Topical Gel)

15 gm tube: ৳ 150.00

Medicine Details

Indications

  • Topical treatment of Acne vulgaris

Pharmacology

  • Combination of lincosamide antibiotic Clindamycin phosphate and retinoid Tretinoin
  • Clindamycin binds with the 50s ribosomal subunit of susceptible bacteria and prevents elongation of peptide chain
  • Clindamycin inhibits the activity of Propionibacterium acne
  • Tretinoin decreases the cohesiveness of follicular epithelial cells and increases turnover

Dosage & Administration

  • Application before sleep and in the morning
  • Wash face gently with mild soap and water before application
  • Application of sunscreen after gel application

Interaction

  • Concomitant use of potentially irritating topical products should be approached with caution
  • Concomitant use of Erythromycin decreases activity of Clindamycin
  • Concomitant use with neuromuscular medicine increases activity of neuromuscular medicine

Contraindications

  • Hypersensitivity to Clindamycin or Tretinoin or any other component of the Gel

Side Effects

  • Erythema
  • Scaling
  • Nasopharyngitis
  • Dry skin
  • Cough
  • Sinusitis
  • Diarrhea

Pregnancy & Lactation

  • Special caution while applying to a nursing mother

Precautions & Warnings

  • Avoid application to eyes, nose, ear, lips, cut, burn, and other infections
  • Keep away from sunlight after application

Therapeutic Class

  • Topical antibiotic & retinoid preparations

Storage Conditions

  • Keep below 25°C temperature
  • Keep away from light & moisture
  • Keep out of the reach of children

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