Melatrin 0.01%+4%+0.05% (Cream)

30 gm tube: ৳ 200.00

Medicine Details

Category Details
Generic Fluocinolone acetonide hydroquinone tretinoin
Company Ziska pharmaceuticals ltd

Indications

  • Short-term treatment of moderate to severe melasma of the face
  • Use a sunscreen of at least SPF 30 or more

Pharmacology

  • Contains Fluocinolone Acetonide, Hydroquinone, and Tretinoin
  • Mechanism of action in the treatment of melasma is unknown
  • Fluocinolone Acetonide is a corticosteroid for topical dermatological use
  • Hydroquinone interrupts one or more steps in the tyrosine-tyrosinase pathway of melanin synthesis
  • Tretinoin is a keratolytic agent

Dosage & Administration

  • Should be applied once daily at night
  • Applied at least 30 minutes before bedtime
  • Use sunscreen and wear protective clothing during the day
  • Avoid sunlight exposure
  • Pediatric use safety and effectiveness not established

Interaction

  • Avoid medicated or abrasive soaps and cleansers
  • Avoid cosmetics with drying effects
  • Avoid products with high concentration of alcohol
  • Avoid concomitant use of medications with photosensitizing effects

Contraindications

  • Contraindicated in individuals with a history of hypersensitivity, allergy, or intolerance to the product or any of its components

Side Effects

  • Severe allergic reactions may occur
  • Skin may develop redness, peeling, burning, dryness, or itching

Pregnancy & Lactation

  • Pregnancy Category C
  • Contains teratogen tretinoin
  • No adequate and well controlled studies in pregnant women
  • Caution should be exercised when administered to nursing women

Precautions & Warnings

  • Hydroquinone and Tretinoin may cause mild to moderate irritation
  • Local irritation such as skin reddening, peeling, burning sensation, dryness, and pruritus may be expected
  • Transient skin reddening or mild burning sensation does not preclude treatment
  • Systemic absorption of topical corticosteroids can produce reversible HPA axis suppression

Therapeutic Class

  • Hydroquinone Preparations

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Do not freeze
  • Keep out of reach of children

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