Ivaten 5 mg (Tablet)
Unit Price: ৳ 30.00 (1 x 10: ৳ 300.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ivabradine |
| Company | Drug international ltd |
| Also available as |
Indications
- Symptomatic treatment of chronic stable angina pectoris in coronary artery disease patients with normal sinus rhythm
- In patients unable to tolerate or with a contra-indication to the use of beta-blockers
- In combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose and whose heart rate is > 60 bpm
Pharmacology
- Pure heart rate lowering agent
- Selective and specific inhibition of the cardiac pacemaker I f current
- Decreases heart rate and cardiac workload
- Prolongs diastole allowing increased coronary artery perfusion
- No effect on intra-atrial, atrioventricular or intraventricular conduction times, nor on myocardial contractility or ventricular repolarization
Dosage & Administration
- Usual recommended starting dose of 5 mg twice daily
- May be increased to 7.5 mg twice daily after 3-4 weeks
- Usual dose is 1 tablet in the morning and 1 tablet in the evening during meals
- Adjust dosage if heart rate decreases persistently below 50 bpm
- Lower starting dose for elderly and exercise caution in hepatic impairment
- Not recommended for use in children and adolescents
Interaction
- Not recommended with QT wave prolonging medicinal products
- Close cardiac monitoring needed if concomitant use is necessary
Contraindications
- Hypersensitivity to Ivabradine or excipients
- Resting heart rate below 60 bpm before treatment
- Cardiogenic shock, acute myocardial infarction, severe hypotension, severe hepatic insufficiency, sick sinus syndrome, sino-atrial block, heart failure, pacemaker dependent, unstable angina, 3rd degree AV block
- Combination with strong cytochrome P-450 3A4 inhibitors
Side Effects
- Visual symptoms, blurred vision, bradycardia, 1st degree AV block, ventricular extrasystoles, headaches, dizziness
Pregnancy & Lactation
- Contraindicated during pregnancy due to limited data
- Contraindicated during breastfeeding due to excretion in milk
Precautions & Warnings
- Mild to moderate hypotension, atrial fibrillation, patients with congenital QT syndrome or treated with QT wave prolonging medicinal products, Moderate hepatic insufficiency, severe renal insufficiency
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children