Donadin 6% w/w (Cream)

20 gm tube: ৳ 26.00

Medicine Details

Category Details
Generic Povidone iodine
Company Ibn sina pharmaceuticals ltd
Also available as

Indications

  • Adjunct to systemic therapy for primary or secondary topical infections
  • Treatment of infected surgical incisions
  • Management of infected decubitus or stasis ulcers
  • Control of pyodermas
  • Management of secondarily infected dermatoses
  • Prevention of microbial contaminations in burns and incisions
  • Degerming skin in hyperalimentation, umbilical area, or circumcision
  • Prevention of infections in abrasions, minor cuts, and wounds
  • Treatment of surface infections and seborrhea
  • Preoperative and postoperative scrubbing and washing of hospital operating room and equipments
  • Disinfection of wounds, burns, lacerations, and abrasions
  • Prophylactic anti-infective agent in house, hospital & office procedures
  • Postoperative application to incisions to help prevent infection
  • Management of oral moniliasis, bacterial and mycotic skin infections, decubitus & stasis ulcers
  • Preoperative swab in the mouth & throat
  • Treatment of acute mucosal infections of the mouth and pharynx
  • Oral hygiene prior to, during and after dental and oral surgery

Pharmacology

  • Complex of iodine and organic polymer (povidone iodine)
  • Prolongs germicidal activity of iodine by liberating elemental iodine slowly
  • Rapid microbicidal activity against bacteria, protozoa, viruses, and fungi/yeasts
  • Sporicidal
  • Non-staining and active in the presence of soap, blood, serum, pus, mucosal secretions, and water

Dosage & Administration

  • Apply cream/ointment once or twice daily for up to 14 days for treatment of infection
  • Apply cream/ointment once or twice a week for prevention of infection
  • Apply solution as often as needed as paint, spray, or wet soak
  • Use gargle & mouthwash undiluted or diluted with warm water, up to 4 times daily for up to 14 consecutive days
  • Apply surgical scrub as per specific instructions for preoperative and postoperative washing
  • Apply powder as a light dusting to the affected area

Interaction

  • Exhibits interaction with strong alkali, sodium thiosulphate, sodium metabisulphite, and thiomersal
  • Concurrent lithium therapy may exhibit a hypothyroidic effect

Contraindications

  • May cause hypersensitivity reactions
  • Avoid regular use in patients with thyroid disorders or those receiving lithium therapy
  • Assess serum iodide levels in severely burnt patients

Side Effects

  • May cause hypersensitivity reactions and irritation of the skin and mucous membranes
  • May produce systemic adverse effects in severe burns or large denuded areas
  • May interfere with thyroid function tests

Pregnancy & Lactation

  • Not recommended for use during pregnancy
  • Usually compatible with breastfeeding (as per American Academy of Pediatrics)
  • Not recommended for use in pregnant and lactating women for gargle & mouthwash and surgical scrub
  • No experience regarding safety in human pregnancy or lactation for povidone eye drops

Precautions & Warnings

  • Special caution in case of deep or puncture wounds, serious burns, or broken skin
  • Avoid prolonged exposure in preoperative prepping
  • Avoid regular use in patients on concurrent lithium therapy
  • Avoid regular use in children under 6 years of age
  • Caution when used on known iodine sensitivity
  • Careful application for patients with blurred vision after instillation of eye drops

Therapeutic Class

  • Iodine compounds (anti-septic preparations)

Storage Conditions

  • Store below 25°C
  • Do not freeze
  • Store in a cool and dry place, protected from light
  • Keep out of the reach of children
  • Do not touch the ophthalmic solution dropper tip to any surface
  • Do not use after one month of the first opening

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