Povin 5% w/w (Ointment)

10 gm tube: ৳ 15.10

Medicine Details

Indications

  • Adjunct to systemic therapy for topical infections
  • Infected surgical incisions
  • Infected decubitus or stasis ulcers
  • Pyodermas
  • Secondarily infected dermatoses
  • Infected traumatic lesions
  • Prevention of microbial contaminations in burns and incisions
  • Degerming skin in hyperalimentation, the umbilical area or circumcision
  • Preventing infections in abrasions, minor cuts, and wounds
  • Acute mucosal infections of the mouth and pharynx
  • Oral hygiene prior to, during, and after dental and oral surgery
  • Antiseptic skin cleanser for preoperative and postoperative scrubbing
  • Treatment of surface infections and seborrhea
  • Preoperative prepping of operative site, including the vagina
  • Disinfection of wounds, burns, lacerations, and abrasions
  • Gargle and mouthwash for the treatment of dry eye conditions including keratoconjunctivitis sicca
  • Gargle and rinse with undiluted or diluted solution
  • Surgical scrub for preoperative and postoperative washing by surgeons
  • Topical application for superficial wounds, minor cuts, burns, and abrasions
  • Symptomatic treatment of dry eye conditions

Pharmacology

  • Complex of iodine and povidone polymer
  • Lower toxicity than elemental iodine
  • Rapid microbicidal activity
  • Activity against Gram-positive and Gram-negative bacteria, protozoa, viruses, and fungi/yeasts
  • Sporicidal
  • Non-staining
  • Active in the presence of soap, blood, serum, pus, mucosal secretions, and water

Dosage & Administration

  • Apply once or twice daily for a maximum of 14 days
  • Apply once or twice a week for prevention of infection
  • Apply full strength as paint, spray, or wet soak
  • Gargle or rinse with up to 10 mL for up to 30 seconds without swallowing
  • Repeat up to four times daily for up to 14 consecutive days
  • Apply a light dusting of powder to the affected area
  • Instill 1 drop 4 times daily into the conjunctival sac

Interaction

Exhibits interaction with strong alkali, sodium thiosulphate, sodium metabisulphite, and thiomersal. Concurrent lithium therapy exhibits hypothyroidic effect.

Contraindications

  • Hypersensitivity reactions
  • Avoid regular use in patients with thyroid disorders or receiving lithium therapy
  • Assess serum iodide levels in severely burnt patients
  • Avoid use in serious cavities and in children under the age of 2 years

Side Effects

  • Hypersensitivity reactions
  • Skin and mucous membrane irritation
  • Systemic adverse effects in severe burns or large denuded skin areas
  • Interference with thyroid function tests

Pregnancy & Lactation

  • Not recommended during pregnancy due to iodine absorption affecting fetal thyroid
  • Usually compatible with breastfeeding
  • Avoid regular use in pregnant and lactating women

Precautions & Warnings

  • Consult physician for deep wounds, puncture wounds, or serious burns
  • Avoid pooling of solution beneath the patient during preoperative prepping
  • Special caution for broken skin applications in patients with pre-existing renal insufficiency
  • Avoid regular use in patients on concurrent lithium therapy

Therapeutic Class

Iodine compounds (Antiseptic Preparations)

Storage Conditions

Store below 25°C, do not freeze, and protect from light. Keep out of reach of children. Do not touch the ophthalmic solution dropper tip to any surface.

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