Povisep 6% w/w (Cream)

5 gm tube: ৳ 22.00

Medicine Details

Indications

  • Therapeutically used as an adjunct to systemic therapy
  • Treatment of primary or secondary topical infections
  • Treatment of infected surgical incisions
  • Treatment of infected decubitus or stasis ulcers
  • Treatment of pyodermas
  • Treatment of secondarily infected dermatoses
  • Prevention of microbial contaminations in burns and incisions
  • Degerming skin in hyperalimentation, umbilical area, or circumcision
  • Prevention of infections in abrasions, minor cuts, and wounds
  • Treatment of seborrhea
  • Preoperative and postoperative scrubbing and washing of hospital operating room and equipment
  • Preoperative prepping of operative site, including the vagina
  • Disinfection of wounds, burns, lacerations, and abrasions
  • Prophylactic anti-infective agent in house, hospital & office procedures
  • Postoperative application to incisions to help prevent infection
  • Treatment of oral moniliasis (thrush), bacterial and mycotic skin infections, decubitus & stasis ulcers
  • Preoperative swab in the mouth & throat
  • Treatment of acute mucosal infections of the mouth and pharynx
  • Oral hygiene prior to, during and after dental and oral surgery

Pharmacology

  • A complex of iodine and an organic polymer, povidone
  • Superior to ordinary elemental iodine
  • Prolongs the germicidal activity of iodine
  • Rapid microbicidal activity against bacteria, protozoa, viruses, and fungi/yeasts
  • Sporicidal
  • Non-staining
  • Active in the presence of soap, blood, serum, pus, mucosal secretions, and water

Dosage & Administration

  • Cream or ointment: Apply once or twice daily for a maximum of 14 days
  • Cream or ointment: Apply once or twice a week for as long as necessary for prevention
  • Solution: Apply full strength as often as needed as paint, spray, or wet soak
  • Gargle & Mouthwash: Use undiluted or diluted with warm water, gargle or rinse up to 10 mL for up to 30 seconds without swallowing
  • Surgical Scrub: Preoperative and postoperative washing by operating personnel and patients
  • Powder: Apply a light dusting to affected area
  • Ophthalmic Solution: 1 drop 4 times daily or as required

Interaction

  • Exhibits interaction with strong alkali, sodium thiosulphate, sodium metabisulphite, and thiomersal
  • Concurrent lithium therapy may exhibit hypothyroidic effect

Contraindications

  • Can cause hypersensitivity reactions
  • Avoid regular use in patients with thyroid disorders or receiving lithium therapy
  • Assess serum iodide levels in severely burnt patients
  • Avoid use in serious cavities
  • Avoid use in children under the age of 2 years

Side Effects

  • May cause hypersensitivity reactions
  • Irritation of the skin and mucous membranes
  • May produce systemic adverse effects in severe burns or large denuded skin areas
  • May interfere with thyroid function tests

Pregnancy & Lactation

  • Not recommended for use during pregnancy
  • Possibility of absorption of sufficient iodine to affect the fetal thyroid
  • Usually compatible with breastfeeding (consult a physician)
  • Avoid regular use in pregnant and lactating women
  • Not recommended for use in human pregnancy or lactation except for compelling reasons

Precautions & Warnings

  • In case of deep or puncture wounds or serious burns, consult a physician
  • Avoid 'pooling' beneath the patient during preoperative prepping
  • Prolonged exposure to wet solution may cause irritation or severe skin reactions
  • Regular use of Gargle & Mouthwash should be limited to 14 days
  • Caution when applying to patients with pre-existing renal insufficiency
  • Care must be taken when used on known iodine sensitivity

Therapeutic Class

  • Iodine compounds (Anti-septic Preparations)

Storage Conditions

  • Store below 25°C and do not freeze
  • Store in a cool, dry place, protected from light
  • Keep out of the reach of children
  • Do not touch the ophthalmic solution dropper tip to any surface
  • Do not use it after one month of the first opening

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