Rupenta 10 mg (Tablet)
Unit Price: ৳ 10.03 (3 x 10: ৳ 300.90)
Strip Price: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Rupatadine fumarate |
| Company | Orion pharma ltd |
Indications
- Symptomatic treatment of Seasonal & Perennial Allergic Rhinitis
- Symptomatic treatment of Urticaria
Pharmacology
- Long-acting non-sedative antagonist of histamine H1-receptors
- Antagonizes platelet activating factor (PAF)
- Inhibits degranulation of mast cells
- Inhibition of release of cytokines
Dosage & Administration
- Recommended dose for adults and adolescents (over 12 years) is 10 mg once a day
- Can be taken with or without food
- Specific doses for children based on weight
Interaction
- Increased systemic exposure with concomitant administration of ketoconazole or erythromycin
- Caution required when co-administered with statins, CNS depressants or alcohol
- Grapefruit and Grapefruit juice should not be taken simultaneously
Contraindications
- Hypersensitivity to Rupatadine or any of the excipients
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Therapeutic Class
- Non-sedating antihistamines
Chemical Structure
- Molecular Formula: C26H26ClN3
Common Questions
- Rupenta 10 mg Tablet is H1-receptors antagonist
- Commonly used to treat seasonal & perennial allergic rhinitis and urticaria
- Maybe unsafe to use during pregnancy
- Caution should be advised in patients with renal impairment
- The onset of action is within 75 minutes after administration
- Duration of action is 8 to 10 hrs
Side Effects
- Common: Asthenia, dizziness, drowsiness
- Uncommon: Appetite increased, arthralgia, back pain
- Rare: Palpitations, tachycardia
Pregnancy & Lactation
- No clinical data available on the exposure of Rupatadine during pregnancy
- Not recommended for use during lactation unless potential benefits justify the potential risk to the infant
Precautions & Warnings
- Use with caution in patients with known prolongation of the QT interval
- Caution in elderly patients (65 years and older)
- Not recommended in patients with impaired kidney or liver function
Overdose Effects
- Most common adverse reaction is somnolence
- Symptomatic treatment together with required supportive measures should be given in case of accidental ingestion of very high doses
Use in Special Populations
- Use with caution in elderly
- Neither safety nor efficacy established in patients less than 12 years of age
- Not recommended in patients with renal or hepatic insufficiency