Rupin 5 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Rupatadine fumarate |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Seasonal & Perennial Allergic Rhinitis
- Urticaria
Pharmacology
- Long-acting non-sedative histamine H1-receptors antagonist
- Antagonizes platelet activating factor (PAF)
- Inhibition of mast cell degranulation
- Inhibition of cytokine release
Dosage & Administration
- Adult dose: 10 mg once a day
- Children aged 2 to 11 years: Dosage based on weight
Interactions
- Ketoconazole and erythromycin increase systemic exposure
- Caution with statins, CNS depressants, and alcohol
- Avoid grapefruit and grapefruit juice
Contraindications
- Hypersensitivity to Rupatadine or excipients
Side Effects
- Common: Asthenia, dizziness, drowsiness
- Uncommon: Appetite increased, back pain, diarrhea, dry throat, nausea
- Rare: Palpitations, tachycardia
Pregnancy & Lactation
- Not recommended during pregnancy and lactation
Precautions & Warnings
- Caution in patients with prolongation of the QT interval
- Caution in elderly patients
- Not recommended in patients with impaired kidney or liver function
Use in Special Populations
- Elderly: Caution advised
- Children: Safety and efficacy not established for those under 12 years
- Renal or hepatic insufficiency: Not recommended
Overdose Effects
- Most common adverse reaction: somnolence
- Symptomatic treatment required for high doses
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Store in cool, dry place below 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C26H26ClN3
Common Questions
- Used for treating seasonal & perennial allergic rhinitis and urticaria
- Pregnancy warnings
- Breast-feeding precautions
- Impact on kidney function
- Impact on liver function
- Onset of action within 75 minutes
- Duration of effect: 8 to 10 hrs