Elfexo 120 mg (Tablet)
Unit Price: ৳ 7.00 (30's pack: ৳ 210.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Improves health-related quality of life
- Relief of symptoms associated with chronic idiopathic urticaria
- Reduces the signs and symptoms of chronic idiopathic urticaria
- Improves work/activity productivity
Pharmacology
- Responsible for mediating hypersensitivity and allergic reactions
- Binding to H1 receptors results in release of pro-inflammatory cytokines
- Considered an "inverse agonist" of the H1 receptor
- Potent and selective affinity for H1 receptors
- No evidence of carrying antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- Unlikely to cause significant CNS effects
Dosage & Administration
- Recommended dosage for adults and children 12 years and older
- Different dosages for allergic rhinitis and chronic idiopathic urticaria
- Dosage adjustments for impaired renal function
- Different dosages for children in different age groups
- Different dosages for tablet and suspension forms
Interaction
- No hepatic biotransformation
- Potential interaction with erythromycin and ketoconazole
- No interaction between fexofenadine and omeprazole
- Reduction in bioavailability when co-administered with antacids
- Recommended time gap between administration and antacid use
Contraindications
- Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients
Side Effects
- Reported frequency rating and categorization of undesirable effects
- Range of reported undesirable effects in clinical trials and post-marketing surveillance
- Adverse reactions related to nervous system, gastrointestinal disorders, immune system, psychiatric disorders, cardiac disorders, and skin/subcutaneous tissue disorders
Pregnancy & Lactation
- No adequate data from the use of Fexofenadine hydrochloride in pregnant women
- Limited animal studies showing no direct or indirect harmful effects
- Not recommended for mothers breast-feeding their babies
- No human data on the effect of Fexofenadine hydrochloride on fertility
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Administered with care in special groups
- Warning for patients with a history of or ongoing cardiovascular disease
- Unlikely to produce an effect on the ability to drive or use machines
- Suggested caution in identifying individual response before driving or performing tasks
Use in Special Populations
- Altered pharmacokinetics in individuals with renal impairment
- Recommended starting dose in patients with decreased renal function
- Moderate to severe hepatic disease does not substantially affect the pharmacokinetics
- Similar adverse events in elderly patients compared to patients under 65 years of age
- Altered pharmacokinetics in individuals over 65 years of age
Overdose Effects
- Reported adverse reactions with overdose of Elfexo
- Reports of administered doses without clinically significant adverse reactions
- Recommended standard measures for overdose
- Recommendation against haemodialysis for removing Elfexo from blood
Therapeutic Class
- Belongs to the category of non-sedating antihistamines
Storage Conditions
- Recommendation to keep in a dry place away from light and heat
- Advisory to keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
- Representation of chemical structure
Common Questions about Elfexo 120 mg Tablet
- Description of Elfexo 120 mg Tablet as an antihistamine
- Uses including treatment of allergic rhinitis and urticaria
- Reported side effects such as Vomiting, Headache, Coughing, Diarrhea, Painful menstruation, Pain in the arms and legs, Hives and redness of skin, Swelling of face, lips, eyelids, tongue, hands, and feet
- Instructions for storage and disposal
- Potential for causing sleepiness and advisories against overdose
- Onset of action and relief of symptoms for outdoor and indoor allergies
- Guidance for coping with dizziness and potential interactions with antacids
- Instruction for intake as recommended by the doctor
- Advisory regarding consumption of certain juices and potential heart problems
- Quick Tips for users including medication effects, precautions, and dietary restrictions