Fexotab 180 mg (Tablet)

Title, Categories and Description

• Fexotab 180 mg Tablet
• Non-sedating antihistamines
• Relief of symptoms associated with seasonal and perennial allergic rhinitis
• Relief of symptoms associated with chronic idiopathic urticaria
• Blocks histamine in the body during an allergic reaction
• Improves health-related quality of life
• Works by preventing activation of H1 receptors
• No evidence of carrying antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
• Does not cross the blood-brain barrier
• Indicated for adults and children 12 years of age and older
• Dosage available in 30 mg, 60 mg, 120 mg, and 180 mg tablets
• Dosage available in 5 ml suspension
• Recommended storage in a dry place away from light and heat
• Keep out of the reach of children
• Molecular Formula: C32H39NO4

Indications

• Relief of symptoms associated with seasonal and perennial allergic rhinitis in adults and children 12 years of age and over
• Relief of symptoms associated with chronic idiopathic urticaria in adults and children 12 years of age and older
• Symptoms treated effectively include sneezing, rhinorrhea, lacrimation, itchy, red eyes and itchy nose/palate/throat

Pharmacology

• Works by stabilizing the inactive form of the H1 receptor

Dosage & Administration

• Adults and children 12 years and older: Tablet - 60 mg twice daily or 120 mg once daily or 180 mg once daily
• Children from 6 to 11 years: Tablet - 30 mg twice daily or 60 mg once daily
• Children from 2 to 11 years: Suspension - 30 mg or 5 ml twice daily

Interaction

• Coadministration with erythromycin or ketoconazole may increase the level of fexofenadine in plasma

Contraindications

• Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

• Common: headache, drowsiness, dizziness, nausea
• Uncommon: fatigue
• Hypersensitivity reactions, chest tightness, insomnia, sleep disorders, tachycardia, palpitations, diarrhea, rash

Pregnancy & Lactation

• Should not be used during pregnancy unless clearly necessary
• Not recommended for mothers breast-feeding their babies

Precautions & Warnings

• Administered with care in older people and renally or hepatically impaired patients
• Patients with a history of or ongoing cardiovascular disease should be warned about potential adverse reactions

Use in Special Populations

• Dose adjustment in patients with decreased renal function
• No substantial effect on the pharmacokinetics of fexofenadine in moderate to severe hepatic disease

Overdose Effects

• Reported effects include dizziness, drowsiness, fatigue, and dry mouth
• Maximum tolerated dose not established
• Standard measures should be considered to remove any unabsorbed medicinal product

Chemical Structure

• Molecular Formula: C32H39NO4

Common Questions about Fexotab 180 mg Tablet

• Antihistamine, blocks histamine in the body during an allergic reaction
• Used for the treatment of allergic rhinitis and urticaria
• Relieves allergy symptoms such as runny nose, itching eyes/nose, sneezing, hives, and itching
• Reported side effects include vomiting, headache, coughing, diarrhea, painful menstruation, hives, and redness of skin
• Should be kept in a cool dry place and in its original pack, out of reach of children and pets
• Can cause sleepiness as a common side effect
• Starts working within 1 hour of consumption
• Can help relieve symptoms caused by outdoor and indoor allergens
• Cautions against heavy machinery or driving if feeling dizzy
• Should not be used in combination with antacids
• No effect on the ability to drive or use machines
• Less likely to make you feel sleepy than some other similar medicines

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