Xofena 30 mg/5 ml (Oral Suspension)
50 ml bottle: ৳ 48.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Asiatic laboratories ltd |
| Also available as |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Improves health-related quality of life in allergic rhinitis patients
- Relief of symptoms associated with chronic idiopathic urticaria
- Reduces signs and symptoms of chronic idiopathic urticaria
- Improves health-related quality of life in chronic idiopathic urticaria patients
Pharmacology
- Responsible for mediating hypersensitivity and allergic reactions
- Inhibits degranulation of mast cells and basophils
- Blocks release of histamine and inflammatory mediators
- Potent and selective affinity for H1 receptors
- No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
- Does not cross the blood-brain barrier
Dosage & Administration
- Adult dosage: 60 mg twice daily or 120 mg/180 mg once daily
- Dosage for impaired renal function: 60 mg/30 mg once daily
- Children 6-11 years: 30 mg/60 mg once daily
- Children < 2 years: 30 mg or 5 ml twice daily
- Dosage for impaired renal function in children: 30 mg or 5 ml once daily
Interaction
- No hepatic biotransformation
- Coadministration with erythromycin or ketoconazole increases fexofenadine levels
- No interaction between fexofenadine and omeprazole
- Antacid containing aluminium and magnesium hydroxide reduces bioavailability
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride
Side Effects
- Common: headache, drowsiness, dizziness, nausea
- Uncommon: fatigue
- Hypersensitivity reactions, tachycardia, palpitations, diarrhea, rash, urticaria, pruritus
Pregnancy & Lactation
- Limited data on use in pregnant women
- No data on effect on fertility
- Not recommended for breastfeeding mothers
Precautions & Warnings
- Limited data in older people and renally/hepatically impaired patients
- Administer with care in special groups
- Warn patients with history of cardiovascular disease
- Unlikely to produce significant effects on ability to drive or use machines
- No significant effects on central nervous system function
Use in Special Populations
- Altered pharmacokinetics in individuals with renal impairment
- Moderate to severe hepatic disease does not substantially affect pharmacokinetics
- Similar adverse events in elderly patients
Overdose Effects
- Dizziness, drowsiness, fatigue, dry mouth
- No clinically significant adverse reactions up to 800 mg single doses
- Symptomatic and supportive treatment recommended
Therapeutic Class
- Non-sedating antihistamines
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C32H39NO4
Common Questions about Xofena 30 mg/5 ml Suspension
- Blocks histamine production during allergic reactions
- Relieves symptoms of allergic rhinitis and urticaria
- Reported side effects include Vomiting, Headache, Coughing, Diarrhea, Hives, redness of skin, Swelling
- Store in a cool dry place and in its original pack
- May cause sleepiness as a common side effect
- Starts working within 1 hour of consumption
- Can relieve symptoms of outdoor and indoor allergies
- Requires caution and rest if feeling dizzy after consumption
- Should not be used in combination with antacids
- Take as recommended by the doctor and avoid certain fruit juices while on a course of the medication
- Exercises caution for those with heart disorders
- Quick Tips: Follow dosage instructions, avoid certain fruit juices, manage nausea, avoid combination with antacids