Neobac (5 mg+500 IU)/gm (Ointment)

10 gm tube: ৳ 25.00

Medicine Details

Indications

  • Treatment of topical bacterial infections
  • Effective in atopic dermatitis
  • Effective in neurodermatitis
  • Useful in pyodermas
  • Adjunct in systemic antibiotic therapy

Pharmacology

  • Bacitracin inhibits bacterial cell wall synthesis
  • Active against gram-positive bacteria
  • Active against some gram-negative species
  • Neomycin binds to the bacterial ribosome
  • Inhibits protein synthesis
  • Active against gram-negative aerobes

Dosage & Administration

  • Ointment application
  • Clean affected area before use
  • Apply 2-3 times daily
  • Dusting powder application
  • Used for superficial skin infections

Interaction

  • Bacitracin Zinc interaction with nephrotoxic drugs
  • Enhanced action of neuromuscular-blocking agents
  • Neomycin Sulphate interaction with aminoglycosides
  • Enhanced toxicity with potent diuretics
  • Impairment of absorption of other drugs

Contraindications

  • Hypersensitivity to any components

Side Effects

  • Well-tolerated in most cases
  • Possible allergic reactions

Pregnancy & Lactation

  • Unestablished safety during pregnancy & lactation
  • Use during pregnancy if benefit justifies risk

Precautions & Warnings

  • Not for use on large open wounds
  • Not for use on severely injured skin
  • Not for use on areas that exude large volumes of fluid
  • Avoid use in otitis external with perforated eardrum

Use in Special Populations

  • Suitable for use in children at adult dose
  • Dose reduction in infants
  • Not recommended for neonates

Therapeutic Class

  • Ophthalmic and Topical antibacterial products

Storage Conditions

  • Store in cool and dry place
  • Keep out of reach of children
  • Protected from light

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