Optison-N 0.1%+0.5% (Ophthalmic Solution)

Indications

• Inflammatory conditions (eg. uveitis, marginal keratitis, allergic conjunctivitis)
• Otitis externa
• Other inflammatory conditions where infection is present or suspected

Pharmacology

• Corticosteroid effective in inflammatory dermatoses
• Effective in psoriasis
• Bactericidal against many bacteria
• Broad spectrum antibiotic
• Inhibits protein synthesis

Dosage & Administration

• Eye Drops: 1 drop instilled every one or two hours
• Ear Drops: 2-3 drops instilled every two or three hours
• Nose Drops: 2-3 drops instilled two or three times daily
• Eye Ointment: Applied thinly and evenly to the conjunctival sac

Contraindications

• Viral, fungal, tuberculous or purulent conditions
• Contra-indicated in glaucoma or herpetic keratitis
• Not to be used if ear drum is perforated

Side Effects

• Acute sensitization to neomycin
• Rise in intra-ocular pressure
• Thinning of the cornea
• Cataract

Pregnancy & Lactation

• Pregnancy Category-Not Classified
• Topical administration to pregnant animals can cause fetal abnormalities
• Topical steroids not to be used extensively in pregnancy

Precautions & Warnings

• Steroids should not be administered to "red eyes" until definitive diagnosis
• Avoid unnecessary topical use of neomycin products

Therapeutic Class

• Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

• Store below 25°C

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