Clonate-NN (0.5 mg+5 mg+1 Lac IU)/gm (Cream)

15 gm tube: ৳ 75.22

Medicine Details

Category Details
Generic Clobetasol propionate neomycin sulphate nystatin
Company Kemiko pharmaceuticals ltd

Indications

  • Short courses treatment of recalcitrant eczemas
  • Neurodermatoses
  • Psoriasis
  • Other inflammatory conditions

Pharmacology

  • Very potent corticosteroid
  • Antibiotic of the aminoglycoside type
  • Antifungal properties
  • Anti-inflammatory activity
  • Interfering with cell membranes

Dosage & Administration

  • Apply sparingly once or twice daily
  • Hyperkeratosis treatment
  • Use caution in elderly and children
  • Not recommended for neonates and infants
  • Max 7 days without supervision
  • Max 4 weeks with review

Interaction

  • Intensify and prolong respiratory depressant effects
  • Minimal systemic exposure expected

Contraindications

  • Rosacea
  • Acne vulgaris
  • Perioral dermatitis
  • Primary cutaneous viral infection
  • Hypersensitivity to the preparation

Side Effects

  • Hypercortisolism with prolonged use
  • Local atrophic changes in the skin
  • Reports of pigmentation changes and hypertrichosis

Pregnancy & Lactation

  • Potential risk of foetal toxicity
  • Not recommended in pregnancy and lactation
  • Safety not established in lactating mothers

Precautions & Warnings

  • Avoid long-term continuous topical therapy
  • Care needed to prevent eye contact
  • Thoroughly wash with water if eye contact occurs
  • Adrenal suppression can occur readily even without occlusion

Overdose Effects

  • Acute overdosage unlikely to occur
  • Features of hypercortisolism may appear in chronic overdosage
  • Discontinue gradually in case of overdose

Therapeutic Class

  • Clobetasol / Clobetasone & Combined Preparations

Storage Conditions

  • Store below 25°C
  • Do not freeze
  • Keep out of reach of children

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