Clovate N (0.5 mg+5 mg+1 Lac IU)/gm (Ointment)
15 gm tube: ৳ 70.21
Medicine Details
Category | Details |
---|---|
Generic | Clobetasol propionate neomycin sulphate nystatin |
Company | Aci limited |
Also available as |
Indications
- Short courses treatment of recalcitrant eczemas
- Neurodermatoses
- Psoriasis (excluding widespread plaque psoriasis) where secondary bacterial infection or fungal infection is present
- Other inflammatory conditions which do not respond satisfactorily to less active steroids
Pharmacology
- Clobetasol Propionate is a very potent corticosteroid
- Neomycin Sulphate is an antibiotic of the aminoglycoside type
- Nystatin is an antifungal that kills fungi and yeasts by interfering with their cell membranes
Dosage & Administration
- Apply sparingly to the affected area once or twice daily until improvement occurs
- Treatment should not be continued for more than 7 days without medical supervision
- This preparation is suitable for use in elderly
- This preparation is suitable for use in children (2 years and over) at the same dose as adults
Interaction
- Neomycin Sulphate can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents
- No hazardous interactions have been reported with use of Clobetasol Propionate or Nystatin
Contraindications
- Rosacea
- Acne vulgaris and perioral dermatitis
- Primary cutaneous viral infection
- Hypersensitivity to the preparation
Side Effects
- Prolonged use of large amount or treatment of extensive areas can result in sufficient systemic absorption to produce the features of hypercortisolism
- Prolonged and intensive treatment with highly active corticosteroid preparations may cause local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels
Pregnancy & Lactation
- The use of the preparation is not recommended in pregnancy and lactation
- The safety of Clobetasol Propionate has not been established in lactating mothers
Precautions & Warnings
- Long-term continuous topical therapy should be avoided where possible
- If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye
Overdose Effects
- Acute overdosage is very unlikely to occur
- In the case of chronic overdosage or misuse, the features of hypercortisolism may appear and in this situation, topical steroids should be discontinued gradually
Therapeutic Class
- Clobetasol / Clobetasone & Combined Preparations
Storage Conditions
- Store below 25°C temperature
- Do not freeze
- Keep out of reach of children
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