Atropine 0.6 mg/ml (Injection)

1 ml ampoule: ৳ 5.00 (50's pack: ৳ 250.00)

Medicine Details

Title

  • Atropine Injection

Categories

  • Medicine
  • Pharmaceuticals
  • Healthcare

Description

  • A medication used to treat various cardiovascular disorders and as an anaesthetic premedication. It is also indicated for anticholinesterase and mushroom poisoning. Atropine has a pharmacological impact on muscarinic acetylcholine receptors, producing anticholinergic effects. It is available in specific dosage strengths for different conditions and should be administered with caution and based on recommended dosage intervals. The drug has contraindications related to specific medical conditions, and its usage during pregnancy and lactation requires careful consideration.

Dosage Strength

  • 0.5mg
  • 1.0mg
  • 2mg
  • 3mg
  • 300mcg
  • 600mcg
  • 100mcg
  • 200mcg
  • 400mcg
  • 500mcg

Dosage Administration

  • Intravenous
  • Intramuscular
  • Subcutaneous
  • Oral

Pharmacological Action

  • Anticholinergic
  • Muscarinic receptor inhibition
  • Vagal activity inhibition

Indications

  • Cardiovascular disorders
  • Anaesthetic premedication
  • Anticholinesterase and mushroom poisoning

Interaction with Other Drugs

  • Tricyclic antidepressants
  • Antispasmodics
  • Antiparkinsonian drugs
  • Antihistamines
  • Phenothiazines
  • Disopyramide
  • Quinidine
  • Metoclopramide

Contraindications

  • Glaucoma
  • Chronic lung disease
  • Unstable cardiac rhythm
  • Prostatic hypertrophy
  • Reflux oesophagitis
  • Paralytic ileus
  • Pyloric stenosis
  • Elderly patients

Side Effects

  • Dry mouth
  • Difficulty in swallowing and talking
  • Thirst
  • Mydriasis
  • Cycloplegia
  • Photophobia
  • Flushing
  • Dry skin
  • Bradycardia
  • Tachycardia
  • Palpitations
  • Arrhythmias
  • Constipation
  • Vomiting

Pregnancy & Lactation Effects

  • Negligible effects on the human uterus
  • Not teratogenic
  • Transfer to breast milk

Precautions & Warnings

  • Caution in children and geriatric patients
  • Avoid giving to patients with diarrhoea or high ambient temperature
  • Cautious use in patients with fever
  • Increased susceptibility in Down's syndrome patients
  • Use with caution in conditions characterized by tachycardia
  • Potential mental confusion in the elderly
  • Care required in patients with hypertension

Therapeutic Class

  • Anticholinergics (antimuscarinics)/ Anti-spasmodics

Storage Conditions

  • Keep below 25°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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