Defiron 100 mg/5 ml (IV Injection or Infusion)

5 ml ampoule: ৳ 350.00

Medicine Details

Category Details
Generic Iron sucrose
Company Square pharmaceuticals plc

Product Title

  • Iron Sucrose Injection USP

Categories

  • Medicine
  • Parenteral Iron Preparations

Description

  • Treatment of Defiron deficiency
  • Rapid Defiron supply
  • Patients intolerant to oral Defiron therapy
  • Patients with active inflammatory bowel disease
  • Chronic kidney disease patients receiving erythropoietin
  • Chronic kidney disease patients not receiving erythropoietin
  • Hemodialysis dependent-chronic kidney disease patients
  • Peritoneal dialysis dependent-chronic kidney disease patients
  • Defiron deficiency anaemia in surgical patients, blood donors, and postpartum patients

Color Options

  • Brown

Dosage for Adults and Elderly

  • 5-10 ml Iron Sucrose Injection (100-200 mg Iron) once to three times a week

Dosage for Children

  • Limited data under study conditions, recommended not to exceed 0.15 ml Iron Sucrose Injection (3 mg Iron) per kg body weight once to three times per week

Administration

  • Intravenous injection
  • Infusion

Interaction

  • Not studied
  • Not to be administered concomitantly with oral iron preparations

Contraindications

  • Evidence of Iron overload
  • Known hypersensitivity to Iron Sucrose or its inactive components
  • Anaemia not caused by Iron deficiency
  • History of allergic disorders including asthma, eczema, anaphylaxis, liver disease, and infections

Side Effects

  • Hypotension
  • Cramps/leg cramps
  • Nausea
  • Headache
  • Vomiting
  • Diarrhea
  • Fever
  • Chest pain
  • Hypertension
  • Hypervolemia
  • Abdominal pain
  • Dyspnea
  • Pneumonia
  • Pruritus
  • Application site reaction
  • Hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy Category-B
  • Caution in nursing women

Precautions & Warnings

  • Periodic monitoring of hematologic and haematinic parameters
  • Withhold in the presence of evidence of tissue Iron overload
  • Caution for hypersensitivity reactions
  • Caution for hypotension

Use in Special Populations

  • Pediatric Use not established
  • No overall differences in safety observed between elderly and younger subjects
  • Injection into dialyser
  • Specific dosage for Hemodialysis Dependent-Chronic Kidney Disease Patients and Non-Dialysis Dependent-Chronic Kidney Disease Patients

Overdose Effects

  • Hemosiderosis
  • Symptoms include hypotension, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema, and cardiovascular collapse
  • Treatment with IV fluids, hydrocortisone, and/or antihistamines

Therapeutic Class

  • Haematinic

Storage Conditions

  • Cool and dry place (15°C-30°C)
  • Protected from light
  • Do not freeze

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