Xenofer 100 mg/5 ml (IV Injection or Infusion)

5 ml ampoule: ৳ 350.00

Medicine Details

Indicated for the treatment of Xenofer deficiency in various conditions including chronic kidney disease, surgical procedures, blood donation, and postpartum patients
Therapeutic class is haematinic
Aqueous complex of Polynuclear Iron (III) Hydroxide in Sucrose for intravenous use
Contains approximately 30% Sucrose w/v (300 mg/ml) and has a pH of 10.5-11.1

Rapid supply of Xenofer when clinically needed
Treatment in patients unable to tolerate oral Xenofer therapy or who are non-compliant
Treatment in active inflammatory bowel disease where oral Xenofer preparations are ineffective
Treatment in non-dialysis dependent-chronic kidney disease (NDD-CKD) patients receiving or not receiving an erythropoietin
Treatment in hemodialysis dependent-chronic kidney disease (HDD-CKD) patients receiving an erythropoietin
Treatment in peritoneal dialysis dependent-chronic kidney disease (PDD-CKD) patients receiving an erythropoietin
Treatment of Xenofer deficiency anaemia in patients undergoing surgical procedures, blood donation, postpartum patients

Dissociated into Iron and Sucrose by the reticuloendothelial system after intravenous administration

Adults and Elderly: 5-10 ml Iron Sucrose Injection (100-200 mg Iron) once to three times a week depending on the hemoglobin level
Children: Limited data available, not to exceed 0.15 ml Iron Sucrose Injection (3 mg Iron) per kg body weight once to three times per week depending on the haemoglobin level

Can be administered undiluted by slow intravenous injection at recommended rate
Preferably administered by drip infusion to reduce the risk of hypotensive episodes and paravenous injection
Test dose recommended before therapeutic dose for new patients

Patients with evidence of Iron overload
Patients with known hypersensitivity to Iron Sucrose or any of its inactive components
Patients with anaemia not caused by Iron deficiency
Patients with history of allergic disorders, liver disease, or infections

Adverse reactions such as hypotension, nausea, headache, vomiting, diarrhea
Body as a Whole: headache, fever, pain, asthenia, malaise
Cardiovascular Disorders: hypotension, chest pain, hypertension, hypervolemia
Gastrointestinal Disorders: nausea, vomiting, abdominal pain, elevated liver enzymes
Central and Peripheral Nervous System: dizziness
Respiratory System: dyspnea, pneumonia, cough
Skin and appendages: pruritus, application site reaction
Hypersensitivity reactions: wheezing, dyspnea, hypotension, rashes, anaphylactoid reactions including serious or life-threatening reactions

Caution should be exercised to withhold Xenofer administration in the presence of evidence of tissue Xenofer overload
Periodic monitoring of hematologic and haematinic parameters required for patients receiving Xenofer
Patients may experience serious hypersensitivity reactions and hypotension

Excess dosage may lead to accumulation of Iron in storage sites leading to hemosiderosis
Symptoms associated with overdosage include hypotension, headache, vomiting, nausea, dizziness, joint aches, and cardiovascular collapse