Feofer 100 mg/5 ml (IV Injection or Infusion)

5 ml ampoule: ৳ 350.00

Medicine Details

Category Details
Generic Iron sucrose
Company Eskayef pharmaceuticals ltd
Also available as
Feofer ds 200 mg injection

Indications

  • Treatment of Feofer deficiency
  • Rapid Feofer supply
  • Patients who cannot tolerate oral Feofer therapy
  • Active inflammatory bowel disease
  • Chronic kidney disease patients receiving an erythropoietin
  • Chronic kidney disease patients not receiving an erythropoietin
  • Non-dialysis dependent-chronic kidney disease patients
  • Hemodialysis dependent-chronic kidney disease patients
  • Peritoneal dialysis dependent-chronic kidney disease patients
  • Feofer deficiency anaemia in surgical patients
  • Feofer deficiency anaemia in blood donors
  • Feofer deficiency anaemia in postpartum patients

Pharmacology

  • Therapeutic class: haematinic
  • Sterile aqueous complex of Polynuclear Iron (III) Hydroxide in Sucrose
  • Approximately 30% Sucrose w/v (300 mg/ml)
  • pH of 10.5-11.1
  • Distribution of Iron in the body
  • Binding of Iron to plasma transferrin
  • Elimination of sucrose through urinary excretion

Dosage

  • 5-10 ml Iron Sucrose Injection (100-200 mg Iron) for adults and elderly
  • Limited data on children
  • Dosage based on hemoglobin level
  • Not to exceed 0.15 ml Iron Sucrose Injection (3 mg Iron) per kg body weight in children

Administration

  • Intravenous injection at recommended rate
  • Maximum of 10 ml Iron Sucrose Injection (200 mg Iron) per injection
  • Test dose before therapeutic dose
  • Infusion recommended to reduce risk of hypotensive episodes
  • Dilution with 0.9% w/v Sodium Chloride for infusion

Interaction

  • Drug-drug interactions not studied
  • Contraindicated with concomitant oral iron preparations

Contraindications

  • Iron overload
  • Hypersensitivity to Iron Sucrose or its components
  • Anaemia not caused by Iron deficiency
  • History of allergic disorders, asthma, eczema, anaphylaxis
  • Liver disease and infections

Side Effects

  • Hypotension
  • Cramps/leg cramps
  • Nausea
  • Headache
  • Vomiting
  • Diarrhea
  • Elevated liver enzymes
  • Dizziness
  • Pruritus
  • Hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy Category-B
  • Caution during nursing

Precautions & Warnings

  • Monitoring of hematologic and haematinic parameters
  • Hypersensitivity reactions
  • Hypotension
  • Caution in pediatric and geriatric use
  • Administration into dialyser for hemodialysis patients

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety observed in elderly subjects
  • Injection into dialyser for hemodialysis
  • Administration for chronic kidney disease patients

Overdose Effects

  • Accumulation of Iron in storage sites leading to hemosiderosis
  • Monitoring of Iron parameters
  • Symptoms associated with overdosage
  • Caution to avoid Feofer overload
  • Treatment of symptoms with IV fluids and medications

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

Cool and dry place, protected from light, Do not freeze

Related Brands