Venofer 100 mg/5 ml (IV Injection or Infusion)

5 ml ampoule: ৳ 322.15 (5's pack: ৳ 1,610.75)

Medicine Details

Category Details
Generic Iron sucrose
Company Vifor international inc switzerland

Indications

  • Treatment of Venofer deficiency
  • Rapid Venofer supply
  • Inflammatory bowel disease treatment
  • Chronic kidney disease treatment
  • Treatment for surgical procedures
  • Anemia treatment

Pharmacology

  • Therapeutic class: haematinic
  • Sterile brown aqueous complex
  • Approximately 30% Sucrose w/v
  • pH of 10.5-11.1
  • Dissociated into Iron and Sucrose
  • Iron distribution in liver and bone marrow
  • Transferrin synthesis increase in Iron deficiency
  • Elimination half-life 6h
  • Total clearance 1.2 L/h
  • Volume distribution in blood and extravascular fluid

Dosage

  • Adult dosage: 5-10 ml Iron Sucrose Injection
  • Children dosage: not to exceed 0.15 ml Iron Sucrose Injection per kg body weight

Administration

  • Intravenous injection
  • Slow intravenous injection rate
  • Maximum 10 ml Iron Sucrose Injection per injection
  • Infusion by drip infusion
  • Dilution with 0.9% w/v Sodium Chloride
  • Infusion time based on Iron content
  • Test dose for new patients

Interaction

  • No studied drug-drug interactions
  • Avoid concomitant oral iron preparations
  • Oral iron therapy should not be given until 5 days after last injection

Contraindications

  • Iron overload evidence
  • Known hypersensitivity to Iron Sucrose
  • Anaemia not caused by Iron deficiency
  • History of allergic disorders, liver disease, infections

Side Effects

  • Hypotension, cramps, nausea, headache, vomiting, diarrhea
  • Various adverse reactions
  • Hypersensitivity reactions including anaphylactoid reactions

Pregnancy & Lactation

  • Pregnancy Category-B
  • Caution during lactation

Precautions & Warnings

  • Periodic monitoring of hematologic and haematinic parameters
  • Caution for hypersensitivity reactions and hypotension
  • Safety and effectiveness in pediatric and geriatric use

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • Administered directly into the venous limb of the dialyser
  • Specific dosages for Hemodialysis Dependent-Chronic Kidney Disease Patients and Non-Dialysis Dependent-Chronic Kidney Disease Patient

Overdose Effects

  • Venofer accumulation leading to hemosiderosis
  • Symptoms of overdosage or rapid infusion
  • Caution to avoid Venofer overload

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store in a cool (15°C-30°C) & dry place
  • Protected from light
  • Do not freeze

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