Difol TR 150 mg+0.5 mg (Capsule (Timed Release))

Unit Price: ৳ 2.00 (6 x 10: ৳ 120.00)
Strip Price: ৳ 20.00

Medicine Details

Indications

  • Treatment and prophylaxis of iron and folic acid deficiency
  • Special focus on pregnancy and lactation

Type

  • Capsule preparation

Ingredients

  • Ferrous sulfate
  • Timed-release form of iron
  • Folic acid

Release Mechanism

  • Timed-release designed for preventing gastric side effects
  • Ensures maximum absorption at the site of absorption

Pharmacological Action

  • Essential for haemoglobin formation
  • Necessary for oxidative processes
  • Absorption from the duodenum and upper jejunum
  • Difference in absorption between ferrous and ferric salt forms
  • Increased requirements during pregnancy

Dosage & Administration

  • 1 capsule daily throughout pregnancy and lactation
  • Higher dosage for some patients based on dietary or other factors

Interaction

  • Diminished absorption when taken concomitantly with tetracyclines
  • Decreased absorption by magnesium trisilicate-containing antacid

Contraindications

  • Patients receiving repeated blood transfusions
  • Patients with anaemias not produced by iron deficiency unless iron deficiency is also present

Side Effects

  • Gastrointestinal irritation
  • Dose-related nausea and epigastric pain

Precautions & Warnings

  • Chelates with antacid and tetracycline
  • Impaired absorption if taken concurrently

Overdose Effects

  • Symptoms of overdosage include epigastric pain, nausea, vomiting, haematemesis, and circulatory collapse
  • Potential for severe complications like encephalopathy, acute hepatic necrosis, and acute renal failure
  • Treatment with desferrioxamine
  • Serum iron level monitoring

Therapeutic Class

  • Iron & Vitamin Combined preparations

Storage Conditions

  • Do not store above 25°C
  • Keep away from light and wet places
  • Keep out of reach of children

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