Cynomin 1000 mcg/ml (IM/SC Injection)

1 ml ampoule: ৳ 5.02 (2 x 5: ৳ 50.16)

Medicine Details

Category Details
Generic Cyanocobalamin
Company Jayson pharmaceuticals ltd
Also available as

Title

  • Cynomin

Categories

  • Vitamin supplement
  • Anemia treatment
  • Pharmaceutical product

Indications

  • Pernicious anemia
  • Vitamin B12 deficiency
  • Thyrotoxicosis
  • Hemorrhage
  • Malignancy
  • Liver or kidney disease
  • Gastric bypass surgery
  • Total or partial gastrectomy
  • Gluten enteropathy or sprue
  • Folic acid deficiency
  • Macrocytic anaemia

Pharmacology

  • Required for erthropoiesis
  • Nucleoprotein synthesis
  • Myelin synthesis
  • Cell reproduction
  • Normal growth
  • Coenzyme for protein synthesis
  • Carbohydrate metabolism
  • Cell replication
  • Hematopoiesis

DosageAndAdministration

  • Usual adult dose for Pernicious Anemia - Initial dose of 1000 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days, Maintenance dose of 100 to 1000 mcg monthly
  • Usual adult dose for B12 Nutritional Deficiency - 25 to 2000 mcg orally daily
  • Usual pediatric dose for B12 Nutritional Deficiency - 0.5 to 3 mcg daily

Interactions

  • Reduced absorption by antibiotics
  • Aminosalicylic acid
  • Anticonvulsants
  • Biguanides
  • Cholestyramine
  • Cimetidine
  • Colchicine
  • K salts
  • Methyldopa

Contraindications

  • Leber's disease
  • Tobacco amblyopia

SideEffects

  • Arthralgia
  • Dizziness
  • Headache
  • Nasopharyngitis
  • Anaphylaxis
  • Angioedema
  • Congestive heart failure
  • Peripheral vascular disease
  • Pulmonary edema
  • Diarrhea
  • Dyspepsia
  • Polycythemia vera
  • Sore throat
  • Nervousness
  • Rhinitis
  • Glossitis
  • Hypoesthesia

PregnancyAndLactation

  • Pregnancy Category A
  • Safe for first trimester of pregnancy
  • Drug distributed in milk during lactation

PrecautionsAndWarnings

  • Intensive treatment may cause hypokalemia and sudden death
  • Use with caution in patients with Leber optic nerve atrophy
  • Thrombocytosis may occur with treatment of severe vitamin B12 megaloblastic anemia

TherapeuticClass

  • Vitamin-B preparations

Related Brands