Colamin 500 mcg (Tablet)

Unit Price: ৳ 4.02 (3 x 10: ৳ 120.60)

Strip Price: ৳ 40.20

Medicine Details

Category	Details
Generic	Mecobalamin
Company	Rangs pharmaceuticals ltd

Indications

Peripheral neuropathy
Diabetic neuropathy
Alcoholic neuropathy
Drug induced neuropathy
Entrapment neuropathy
Lumbago
Intercostal neuralgia
Diabetic retinopathy
Multiple sclerosis
Vertebral syndrome
Parkinson's disease
Alzheimer's disease
Bell's palsy
Megaloblastic anemia due to vitamin B12 deficiency

Pharmacology

Coenzyme form of vitamin B12, cofactor in methionine synthase enzyme, required for myelin integrity, neuronal function, red blood cell formation, DNA synthesis, neuronal lipids synthesis, axonal nerve regeneration, axonal transport, neuroprotective activity

Dosage & Administration

0.5 mg tablet 3 times daily after meal
Injection: 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week; dosage adjustment based on age and symptoms
Maintenance therapy: 1 ampoule at 1 to 3 month intervals. Not recommended for use in children

Interaction

Interacts with neomycin, aminosalicylic acid, histamine H2-antagonists, omeprazole, colchicine, oral contraceptives; consider when performing blood concentration assays

Contraindications

Hypersensitivity to Mecobalamin or other components of the formulation

Side Effects

Rash
Anorexia
Nausea/vomiting
Diarrhea
Headache
Anaphylactoid reaction: decrease in blood pressure or dyspnea
Hot sensation
Diaphoresis
Pain/induration at the site of intramuscular injection; discontinue treatment if necessary

Pregnancy & Lactation

No data available for use in pregnant women & lactating mother; vitamin B12 distributed in breast milk; usually compatible with breast feeding as per the American Academy of Pediatrics

Precautions & Warnings

Not for aimless use for more than one month unless effective
Prolonged use of larger doses not recommended for patients handling mercury or mercury compounds