MB 12 500 mcg/ml (IM/IV Injection)
1 ml ampoule: ৳ 30.20 (1 x 5: ৳ 151.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Mecobalamin |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Peripheral neuropathy
- Diabetic neuropathy
- Alcoholic neuropathy
- Drug induced neuropathy
- Entrapment neuropathy
- Lumbago
- Intercostal neuralgia
- Diabetic retinopathy
- Multiple sclerosis
- Vertebral syndrome
- Parkinson's disease
- Alzheimar's disease
- Bell's palsy
- Treatment of peripheral neuropathies megaloblastic anemia due to vitamin B12 deficiency
Pharmacology
- Cofactor in the enzyme methionine synthase
- Neuronal function
- Red blood cell formation
- DNA synthesis
- Neuronal lipids synthesis
- Regeneration of axonal nerves
- Axonal transport
- Neuroprotective activity
Dosage and administration
- 0.5 mg tablet 3 times daily after meal
- 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week for peripheral neuropathies
- 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week for megaloblastic anemia in adults
- Single administration of 1 ampoule at 1 to 3 month intervals for maintenance therapy for megaloblastic anemia in adults
- Not recommended for use in children
Interactions
- Reduced absorption by neomycin, aminosalicylic acid, histamine H2-antagonists, omeprazole, and colchicine
- Decreased serum concentrations by oral contraceptives
Contraindications
- Hypersensitivity to Mecobalamin or other components of the formulation
Side effects
- Rash
- Anorexia
- Nausea/vomiting
- Diarrhea
- Headache
- Anaphylactoid reaction
- Hot sensation
- Diaphoresis
- Pain/induration at the site of intramuscular injection
Pregnancy and lactation
- No data available for use in pregnant women & lactating mother
- Vitamin B12 distributed into breast milk
- Considered usually compatible with breast feeding by The American Academy of Pediatrics
Precautions and warnings
- Not to be used aimlessly for more than one month unless it is effective
- Prolonged use of larger doses not recommended for patients whose occupation requires handling of mercury or mercury compounds
Therapeutic class
- Drugs for Megaloblastic Anemia
Storage conditions
- Store at room temperature
- Protect from moisture and light