Mecol 500 mcg (Tablet)

Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Mecobalamin
Company Aristopharma ltd

Indications

  • Peripheral neuropathy
  • Diabetic neuropathy
  • Alcoholic neuropathy
  • Drug induced neuropathy
  • Entrapment neuropathy
  • Lumbago
  • Intercostal neuralgia
  • Diabetic retinopathy
  • Multiple sclerosis
  • Vertebral syndrome
  • Parkinson's disease
  • Alzheimer's disease
  • Bell's palsy
  • Megaloblastic anemia due to vitamin B12 deficiency

Pharmacology

  • Cofactor in methionine synthase enzyme
  • Regeneration of methionine from homocysteine
  • Integrity of myelin
  • Neuronal function
  • Red blood cell formation
  • DNA synthesis
  • Neuronal lipid synthesis
  • Regeneration of axonal nerves
  • Promotes axonal transport
  • Neuroprotective activity

Dosage & Administration

  • 0.5 mg tablet
  • 3 times daily after meal
  • IM or IV administration
  • Dose adjustment based on age and symptoms
  • Megaloblastic Anemia dosage reduction after 2 months
  • Use not recommended in children

Interaction

  • Reduced absorption by neomycin
  • Reduced absorption by aminosalicylic acid
  • Reduced absorption by H2-antagonists
  • Reduced absorption by omeprazole
  • Reduced absorption by colchicine
  • Decreased serum concentrations by oral contraceptives

Contraindications

  • Hypersensitivity to Mecobalamin or other components

Side Effects

  • Rash
  • Anorexia
  • Nausea/vomiting
  • Diarrhea
  • Headache
  • Anaphylactoid reaction
  • Decrease in blood pressure
  • Dyspnea
  • Hot sensation
  • Diaphoresis
  • Pain/induration at the site of intramuscular injection

Pregnancy & Lactation

  • No data on use in pregnant women & lactating mother
  • Vitamin B12 distribution into breast milk

Precautions & Warnings

  • Not recommended for aimless use beyond one month
  • Prolonged use not recommended for certain occupational groups

Therapeutic Class

  • Drugs for Megaloblastic Anemia

Storage Conditions

  • Room temperature storage
  • Protection from moisture and light

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