Mecolagin 500 mcg/ml (IM/IV Injection)
1 ml ampoule: ৳ 30.00 (1 x 5: ৳ 150.00)
Medicine Details
Category | Details |
---|---|
Generic | Mecobalamin |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Peripheral neuropathy
- Diabetic neuropathy
- Alcoholic neuropathy
- Drug induced neuropathy
- Entrapment neuropathy
- Lumbago
- Intercostal neuralgia
- Diabetic retinopathy
- Multiple sclerosis
- Vertebral syndrome
- Parkinson's disease
- Alzheimer's disease
- Bell's palsy
- Megaloblastic anemia due to vitamin B12 deficiency
Pharmacology
- Coenzyme form of vitamin B12
- Required for integrity of myelin
- Neuronal function
- Red blood cell formation
- DNA synthesis
- Promotes axonal transport
- Neuroprotective activity
Dosage & Administration
- 0.5 mg tablet 3 times daily after meal
- IM or IV 3 times a week for peripheral neuropathies
- IM or IV 3 times a week for megaloblastic anemia
- Dosage adjustment according to age and severity of symptoms
- Not recommended for use in children
Interaction
- Reduced absorption by neomycin
- Reduced absorption by aminosalicylic acid
- Reduced absorption by histamine H2-antagonists
- Reduced absorption by omeprazole
- Reduced absorption by colchicine
- Decreased serum concentrations by oral contraceptives
Contraindications
- Hypersensitivity to Mecobalamin or other components of the formulation
Side Effects
- Rash
- Anorexia
- Nausea/vomiting
- Diarrhea
- Headache
- Anaphylactoid reaction
- Hot sensation
- Diaphoresis
- Pain/induration at the site of intramuscular injection
Pregnancy & Lactation
- No data available for use in pregnant women and lactating mothers
- Vitamin B12 distributed into breast milk
- Use considered usually compatible with breastfeeding by the American Academy of Pediatrics
Precautions & Warnings
- Not to be used aimlessly for more than one month
- Avoid prolonged use of larger doses for patients handling mercury or mercury compounds
Therapeutic Class
- Drugs for Megaloblastic Anemia
Storage Conditions
- Store at room temperature
- Protect from moisture and light