Mecolagin 500 mcg/ml (IM/IV Injection)

1 ml ampoule: ৳ 30.00 (1 x 5: ৳ 150.00)

Medicine Details

Indications

  • Peripheral neuropathy
  • Diabetic neuropathy
  • Alcoholic neuropathy
  • Drug induced neuropathy
  • Entrapment neuropathy
  • Lumbago
  • Intercostal neuralgia
  • Diabetic retinopathy
  • Multiple sclerosis
  • Vertebral syndrome
  • Parkinson's disease
  • Alzheimer's disease
  • Bell's palsy
  • Megaloblastic anemia due to vitamin B12 deficiency

Pharmacology

  • Coenzyme form of vitamin B12
  • Required for integrity of myelin
  • Neuronal function
  • Red blood cell formation
  • DNA synthesis
  • Promotes axonal transport
  • Neuroprotective activity

Dosage & Administration

  • 0.5 mg tablet 3 times daily after meal
  • IM or IV 3 times a week for peripheral neuropathies
  • IM or IV 3 times a week for megaloblastic anemia
  • Dosage adjustment according to age and severity of symptoms
  • Not recommended for use in children

Interaction

  • Reduced absorption by neomycin
  • Reduced absorption by aminosalicylic acid
  • Reduced absorption by histamine H2-antagonists
  • Reduced absorption by omeprazole
  • Reduced absorption by colchicine
  • Decreased serum concentrations by oral contraceptives

Contraindications

  • Hypersensitivity to Mecobalamin or other components of the formulation

Side Effects

  • Rash
  • Anorexia
  • Nausea/vomiting
  • Diarrhea
  • Headache
  • Anaphylactoid reaction
  • Hot sensation
  • Diaphoresis
  • Pain/induration at the site of intramuscular injection

Pregnancy & Lactation

  • No data available for use in pregnant women and lactating mothers
  • Vitamin B12 distributed into breast milk
  • Use considered usually compatible with breastfeeding by the American Academy of Pediatrics

Precautions & Warnings

  • Not to be used aimlessly for more than one month
  • Avoid prolonged use of larger doses for patients handling mercury or mercury compounds

Therapeutic Class

  • Drugs for Megaloblastic Anemia

Storage Conditions

  • Store at room temperature
  • Protect from moisture and light

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