Mecomin 500 mcg (Tablet)

Unit Price: ৳ 4.00 (50's pack: ৳ 200.00)

Medicine Details

Category	Details
Generic	Mecobalamin
Company	Peoples pharma ltd

Indications

Peripheral neuropathy
Diabetic neuropathy
Alcoholic neuropathy
Drug induced neuropathy
Entrapment neuropathy
Lumbago
Intercostal neuralgia
Diabetic retinopathy
Multiple sclerosis
Vertebral syndrome
Parkinson's disease
Alzheimer's disease
Bell's palsy
Megaloblastic anemia

Pharmacology

Mecobalamin is a coenzyme form of vitamin B12. It is a cofactor in the enzyme methionine synthase, required for myelin integrity, neuronal function, RBC formation, and DNA synthesis. It helps in the synthesis of neuronal lipids, axonal nerves regeneration, promotes axonal transport, and has neuroprotective activity.

Dosage & Administration

Tablet: 0.5 mg tablet 3 times daily after meal. Dosage adjusted according to age and symptoms severity.
Injection:
- 1 ampoule (Mecobalamin 500 mcg) daily, IM or IV 3 times a week for peripheral neuropathies in adults
- 1 ampoule (Mecobalamin 500 mcg) daily, IM or IV 3 times a week for megaloblastic anemia in adults. After 2 months, reduce to a single administration at intervals for maintenance therapy.
Use in Children: Not Recommended

Interaction

Absorption of vitamin B12 from the gastrointestinal tract may be reduced by certain medications.

Contraindications

Hypersensitivity to Mecobalamin or other components of the formulation.

Side Effects

Dermatologic Effects: Rash
Gastrointestinal Effects: Anorexia, nausea/vomiting, diarrhea
Neurologic Effects (CNS): Headache
Others:
- Anaphylactoid reaction: decrease in blood pressure or dyspnea
- Hot sensation
- Diaphoresis
- Pain/induration at the site of intramuscular injection

Pregnancy & Lactation

No data available for mecobalamin use in pregnant women & lactating mothers.

Precautions & Warnings

Mecomin should not be used aimlessly for more than one month unless effective. Prolonged use of larger doses not recommended for patients handling mercury or mercury compounds.