Nerviton 500 mcg (Tablet)

Unit Price: ৳ 4.03 (5 x 10: ৳ 201.50)

Strip Price: ৳ 40.30

Medicine Details

Category	Details
Generic	Mecobalamin
Company	Opsonin pharma ltd
Also available as	Nerviton 500 mcg injection

Indications

Peripheral neuropathy
Diabetic neuropathy
Alcoholic neuropathy
Drug induced neuropathy
Entrapment neuropathy
Lumbago
Intercostal neuralgia
Diabetic retinopathy
Multiple sclerosis
Vertebral syndrome
Parkinson's disease
Alzheimar's disease
Bell's palsy
Megaloblastic anemia due to vitamin B12 deficiency

Pharmacology

Mecobalamin is a coenzyme form of vitamin B12. It is a cofactor in the enzyme methionine synthase, required for integrity of myelin, neuronal function, red blood cell formation, DNA synthesis, and has neuroprotective activity.

Dosage & Administration

Tablet: 0.5 mg tablet 3 times daily after meal. Dosage adjusted according to age and severity of symptoms.
Injection:
- Peripheral Neuropathies: Adult: 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week. Dose may be adjusted. Megaloblastic Anemia: Adult: 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week. After 2 months, reduce to a single administration at 1 to 3 month intervals for maintenance therapy.
- Use in Children: Not Recommended

Interaction

Absorption of vitamin B12 may be reduced by neomycin, aminosalicylic acid, histamine H2-antagonists, omeprazole, and colchicine. Serum concentrations may be decreased by oral contraceptives.

Contraindications

Hypersensitivity to Mecobalamin or other components of the formulation.

Side Effects

Dermatologic Effects: Rash
Gastrointestinal Effects:
- Anorexia
- Nausea/vomiting
- Diarrhea
Neurologic Effects: Headache
Others:
- Anaphylactoid reaction
- Hot sensation
- Diaphoresis
- Pain/induration at the site of intramuscular injection

Pregnancy & Lactation

No specific data available for mecobalamin use in pregnant women & lactating mothers. Vitamin B12 is usually compatible with breastfeeding.

Precautions & Warnings

Nerviton should not be used aimlessly for more than one month unless effective. Prolonged use of larger doses not recommended for patients handling mercury or mercury compounds at work.