Nerviton 500 mcg/ml (IM/IV Injection)

1 ml ampoule: ৳ 30.20 (1 x 5: ৳ 151.00)

Medicine Details

Category Details
Generic Mecobalamin
Company Opsonin pharma ltd
Also available as
Nerviton 500 mcg tablet

Title

Nerviton Tablet

Categories

  • Medicine
  • Health
  • Vitamins & Supplements

Description

Nerviton Tablet is indicated for peripheral neuropathy, diabetic neuropathy, alcoholic neuropathy, drug-induced neuropathy, entrapment neuropathy, lumbago, intercostal neuralgia, diabetic retinopathy, multiple sclerosis, vertebral syndrome, Parkinson's disease, Alzheimer's disease, and Bell's palsy. It is also indicated for the treatment of peripheral neuropathies and megaloblastic anemia due to vitamin B12 deficiency. The pharmacology involves Mecobalamin which is a coenzyme form of vitamin B12 essential for myelin integrity, neuronal function, red blood cell formation, and DNA synthesis. The dosage for tablets is 0.5 mg three times daily after a meal, whereas for injection, it is administered IM or IV 3 times a week. Vitamin B12 absorption may be reduced by certain medications. Nerviton is contraindicated in individuals with hypersensitivity to Mecobalamin. Side effects may include dermatologic effects, gastrointestinal effects, and neurologic effects, among others. It should not be used aimlessly for more than one month unless effective, and the prolonged use of larger doses is not recommended for those handling mercury or mercury compounds. Nerviton belongs to the therapeutic class of drugs for megaloblastic anemia and should be stored at room temperature, protected from moisture and light.

Attributes

  • Indications:
    • Peripheral neuropathy
    • Diabetic neuropathy
    • Alcoholic neuropathy
    • Drug-induced neuropathy
    • Entrapment neuropathy
    • Lumbago
    • Intercostal neuralgia
    • Diabetic retinopathy
    • Multiple sclerosis
    • Vertebral syndrome
    • Parkinson's disease
    • Alzheimer's disease
    • Bell's palsy
    • Megaloblastic anemia due to vitamin B12 deficiency
  • Pharmacology:
    • Coenzyme form of vitamin B12
    • Methyl group at the cobalt
    • Cofactor in methionine synthase enzyme
    • Required for myelin integrity
    • Promotes axonal transport
    • Neuroprotective activity
  • Dosage & Administration:
    • 0.5 mg tablet 3 times daily after meal
    • Injection: 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week for peripheral neuropathies
    • Injection: 1 ampoule (Mecobalamin 500 mcg) daily, administered IM or IV 3 times a week for megaloblastic anemia in adults
  • Interaction:
    • Reduced absorption by neomycin, aminosalicylic acid, histamine H2-antagonists, omeprazole, and colchicine
    • Decreased serum concentrations by oral contraceptives
  • Contraindications:
    • Hypersensitivity to Mecobalamin or other components of the formulation
  • Side Effects:
    • Rash
    • Anorexia
    • Nausea/vomiting
    • Diarrhea
    • Headache
    • Anaphylactoid reaction
    • Hot sensation
    • Diaphoresis
    • Pain/induration at the site of intramuscular injection
  • Pregnancy & Lactation:
    • No data available for use in pregnant women
    • Usually compatible with breastfeeding due to distribution into breast milk
  • Precautions & Warnings:
    • Not to be used aimlessly for more than one month unless effective
    • Prolonged use of larger doses not recommended for patients handling mercury or mercury compounds
  • Therapeutic Class:
    • Drugs for Megaloblastic Anemia
  • Storage Conditions:
    • Store at room temperature
    • Protect from moisture and light

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