Folac 5 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Folic acid |
| Company | Ambee pharmaceuticals ltd |
Indications
- Folac deficiency
- Megaloblastic anemia
- Anemias of nutritional origins, pregnancy, infancy, or childhood
Pharmacology
Folic acid is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase (DHFR). It is needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. It can also normalize high homocysteine levels with the help of vitamin B12.
Dosage & Administration
- Adults:
- Initially: 5 mg daily for 4 months
- Maintenance: 5 mg every 1-7 days depending on the underlying disease
- Children:
- Up to 1 year: 500 mcg/kg daily
- Over 1 year: Same as adult dose
Interaction
None reported
Contraindications
Folic acid is contraindicated in patients who have shown previous intolerance to the drug
Side Effects
Folac is generally well tolerated. Gastro-intestinal disturbances may occur. Hypersensitivity reactions have been reported rarely.
Pregnancy & Lactation
No special precautions are known
Precautions & Warnings
Should be used with caution in patients with folate dependent tumors. Should not be given alone or in conjunction with inadequate vitamin B12 for the treatment of undiagnosed megaloblastic anemia. No harmful results found from short courses of folate
Therapeutic Class
Drugs for Megaloblastic Anemia, Vitamin-B preparations
Storage Conditions
Store below 30°C in a dry place, away from light. Keep out of the reach of children