Epoetin 3000 IU (IV/SC Injection)
3000 IU pre-filled syringe: ৳ 1,480.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis
- Treatment of anemia in Chronic Kidney Disease (CKD) patients not on dialysis
- Treatment of anemia in Zidovudine-treated HIV-infected patients
- Reduction of allogeneic RBC transfusions in patients undergoing elective, noncardiac, nonvascular surgery
- Prevention of anemia of prematurity in infants with low birth weight
Description
- Recombinant human erythropoietin (EPO)
- Expressed in Chinese hamster ovary cells
- Has a 165 amino acid sequence identical to human urinary EPO
- Apparent molecular weight of about 30,400 daltons
Dosage
- Evaluation of Iron Stores and Nutritional Factors
- Monitoring hemoglobin levels before and during treatment
- Considerations for patients with CKD on dialysis
- Considerations for patients with CKD not on dialysis
- Dose adjustments for Zidovudine-treated HIV-infected patients
- Initiation of Erythropoietin alfa in cancer chemotherapy patients
- Dosage and administration for prevention of anemia of prematurity
Administration
- Preparation and Administration guidelines
- Not to shake or use frozen Erythropoietin alfa
- Visual inspection for particulate matter and discoloration
- Discard unused portions of Erythropoietin alfa
Interaction
- Potentiation by the therapeutic administration of a haematinic agent like ferrous sulphate
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Patients with Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- Adverse reactions in Epoetin treated patients
- Specific adverse reactions for patients with CKD, Zidovudine-treated HIV-infected patients, cancer patients on chemotherapy, surgery patients, and premature infants
Pregnancy & Lactation
- Use in pregnant chronic renal failure patients
- Not recommended for pregnant or lactating surgical patients in an autologous blood predonation programme
- Caution in nursing women
Overdose Effects
- Possible effects of Epoetin overdosage
- Management with discontinuation or reduction of Epoetin dosage
- Possible cases of severe hypertension following overdose with ESAs
Therapeutic Class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
- Store at 2°C to 8°C
- Do not freeze or shake
- Store in original package to protect from light