Epoetin 5000 IU (IV/SC Injection)
5000 IU pre-filled syringe: ৳ 2,160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Erythropoietin alfa |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis and not on dialysis
- Treatment of anemia due to Zidovudine in HIV-infected patients
- Treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy
- Reduction of allogeneic RBC transfusions in patients undergoing noncardiac, nonvascular surgery
- Prevention of anemia of prematurity in infants with low birth weight and gestational age
Description
- Recombinant human erythropoietin (EPO)
- Expressed in Chinese hamster ovary cells
- Has a 165 amino acid sequence identical to that of human urinary EPO
- Apparent molecular weight of erythropoietin is about 30,400 daltons
Dosage
- Evaluation of iron stores and nutritional factors before and during treatment
- Monitoring hemoglobin levels frequently when initiating or adjusting therapy
- Dose adjustment based on hemoglobin levels and responsiveness to ESA
- Different dosing recommendations for CKD patients on dialysis and not on dialysis, and Zidovudine-treated HIV-infected patients
Administration
- Preparation and administration precautions for Erythropoietin alfa
- Visual inspection for particulate matter and discoloration prior to administration
- Proper disposal of unused portions
Interaction
- Potentiation of Epoetin effect by haematinic agents such as ferrous sulphate
Contraindications
- Uncontrolled hypertension
- Serious allergic reactions to Erythropoietin alfa
- Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin
Side Effects
- Adverse reactions in patients with CKD, Zidovudine-treated HIV-infected Patients, Cancer Patients on Chemotherapy, Surgery Patients, and Premature infants
Pregnancy & Lactation
- Use considerations for pregnant and nursing women
- Potential risks and benefits in chronic renal failure patients and surgical patients participating in an autologous blood predonation programme
Overdose Effects
- Management of high hemoglobin levels and severe hypertension following Epoetin overdosage
Therapeutic Class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
- Temperature range for storage and protection from light