Nipotin 3000 IU (IV/SC Injection)

3000 IU pre-filled syringe: ৳ 1,400.00

Medicine Details

Category Details
Generic Erythropoietin alfa
Company Aristopharma ltd
Also available as
Nipotin 2000 iu injection Nipotin 4000 iu injection Nipotin 5000 iu injection Nipotin 10000 iu injection

Indications

  • Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis
  • Treatment of anemia in CKD patients not on dialysis
  • Treatment of anemia due to Zidovudine in HIV-infected patients
  • Treatment of anemia due to myelosuppressive chemotherapy
  • Reduction of allogeneic RBC transfusions in noncardiac, nonvascular surgery
  • Prevention of anemia of prematurity in infants

Description

Recombinant human erythropoietin (EPO) with a 165 amino acid sequence

Dosage

  • Evaluation of Iron Stores and Nutritional Factors before treatment
  • Monitoring hemoglobin levels before and during therapy
  • Dosing adjustments based on hemoglobin rate of rise, decline, and responsiveness
  • Initiating and adjusting therapy for CKD patients on dialysis and not on dialysis
  • Dose adjustment for Zidovudine-treated HIV-infected Patients
  • Initiation of Erythropoietin alfa in cancer chemotherapy patients
  • Dosage regimen for prevention of anemia of prematurity in infants

Administration

  • Preparation and administration instructions
  • Recommendations to protect syringe from light
  • Visual inspection prior to administration
  • Discard unused portions of Erythropoietin alfa

Interaction

Potentiation of Nipotin effect by haematinic agents like ferrous sulphate

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Patients with Pure Red Cell Aplasia (PRCA) following previous erythropoietin treatment

Side Effects

  • Adverse reactions in CKD patients
  • Adverse reactions in Zidovudine-treated HIV-infected Patients
  • Adverse reactions in cancer patients on chemotherapy
  • Adverse reactions in noncardiac, nonvascular surgery patients
  • Common fall in serum ferritin values in premature infants

Pregnancy & Lactation

Limited information on use in pregnant and lactating women

Overdose Effects

Potential for hemoglobin levels above desired level; risk of severe hypertension

Therapeutic Class

Drugs for Haemolytic Hypoplastic & Renal Anemia

Storage Conditions

Store at 2°C to 8°C; protect from freezing and light

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