Nipotin 4000 IU (IV/SC Injection)

4000 IU pre-filled syringe: ৳ 1,900.00

Medicine Details

Indications

  • Treatment of anemia in Chronic Kidney Disease (CKD) patients on dialysis and not on dialysis
  • Treatment of anemia in HIV-infected patients receiving Zidovudine
  • Treatment of anemia due to the effects of myelosuppressive chemotherapy
  • Reduction of allogeneic RBC transfusions in patients undergoing elective noncardiac nonvascular surgery
  • Prevention of anemia of prematurity in infants with specific birth weight and gestational age

Description

  • Recombinant human erythropoietin (EPO)
  • Expressed in Chinese hamster ovary cells
  • Has a 165 amino acid sequence identical to human urinary EPO

Dosage

  • Evaluation of iron stores and nutritional factors before and during treatment
  • Monitoring hemoglobin levels at least weekly for CKD patients
  • Consideration of hemoglobin rate of rise, decline, and variability when adjusting therapy
  • Specific starting dose and administration guidelines for CKD patients on dialysis and not on dialysis
  • Starting dose and dose adjustment recommendations for Zidovudine-treated HIV-infected patients
  • Initiation and dosing instructions for patients on cancer chemotherapy

Administration

  • Instructions for preparation and administration
  • Guidelines to not shake or use frozen Erythropoietin alfa
  • Visual inspection for particulate matter and discoloration prior to administration
  • Recommendation to protect syringe from light and discard unused portions

Interaction

  • Potential potentiation by simultaneous administration of a haematinic agent such as ferrous sulphate

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Patients who develop Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin

Side Effects

  • List of adverse reactions observed in Nipotin treated patients in clinical studies

Pregnancy & Lactation

  • Cautionary use in pregnancy and lactation due to limited studies
  • Guidance on considering potential benefits and risks to the fetus and the nursing child

Overdose Effects

  • Potential effects of Nipotin overdosage
  • Management of hemoglobin levels above the desired level
  • Cases of severe hypertension observed following overdosage with ESAs

Therapeutic Class

  • Therapeutic class of Drugs for Haemolytic Hypoplastic & Renal Anemia

Storage Conditions

  • Specific temperature range for storage
  • Instruction to not freeze or shake
  • Guidance to store in original package to protect from light

Related Brands