B-One 100 mg (Tablet)
Unit Price: ৳ 0.74 (100's pack: ৳ 74.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Thiamine hydrochloride |
| Company | Alco pharma ltd |
Indications
- Treatment of thiamine deficiency
- Beriberi
- Wernick's encephalopathy
- Neuritis associated with pregnancy
- Pellagra
- Prophylactic use in low dietary intake
- Prophylactic use in impaired gastrointestinal absorption of thiamine
- Prophylactic use in increased requirements like pregnancy
Pharmacology
- Role as coenzyme for decarboxylation of alpha-ketoglutaric acid
- Affects peripheral nervous system, gastrointestinal tract, and cardiovascular system
- Necessary for optimal growth of infants and children
- Not stored in the body and regularly lost during deficiency
- Adequate daily intake required to maintain normal health
- Well absorption and distribution throughout the body
- Excess ingested thiamine appears in urine
- Plasma half-life of 24 hours
Dosage & Administration
- Prophylaxis dosage: 3 to 10 mg daily
- Mild chronic deficiency dosage: 10 to 25 mg daily
- Severe deficiency dosage: 200 to 300 mg daily
Interaction
- Acts synergistically with other B-complex vitamins
- Reduced potential for causing adverse effects
Contraindications
- No absolute contraindications
- Increased risk of anaphylaxis by repeated parenteral administration
- Mild allergic phenomena as warning signs
- Avoid intravenous administration except in comatose patients
- No need for parenteral administration or excess amounts after correction of deficiency
Side Effects
- No adverse effects when given orally
- Risk of anaphylactic reactions with intravenous or intramuscular administration
- Transient mild soreness at the site of intramuscular administration
Pregnancy & Lactation
- Safe for neonates, children, pregnant, and lactating women
Therapeutic Class
- Vitamin-B preparations
Storage Conditions
- Protection from light and moisture