G-Vitamin B1 100 mg (Tablet)
Unit Price: ৳ 0.60 (1 x 100: ৳ 60.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Thiamine hydrochloride |
| Company | Gonoshasthaya pharma ltd |
Indications
- Treatment of thiamine deficiency
- Beriberi treatment
- Wernick's encephalopathy treatment
- Neuritis treatment
- Pellagra treatment
- Prophylactic use for low dietary intake
- Prophylactic use for impaired gastrointestinal absorption of thiamine
- Prophylactic use for increased requirements
Pharmacology
- Coenzyme for decarboxylation of α-ketoglutaric acid
- Affects peripheral nervous system
- Affects gastrointestinal tract
- Affects cardiovascular system
- Necessary for optimal growth of infants and children
- Not stored in the body
- Regularly lost from tissues during deficiency
- Required daily intake
- Deficiency leads to fatigue
- Deficiency leads to anorexia
- Deficiency leads to gastrointestinal disturbance
- Deficiency leads to tachycardia
- Deficiency leads to irritability
- Deficiency leads to neurological symptoms
- Well absorbed from gastrointestinal tract
- Widely distributed throughout the body
- Rapid absorption from upper small intestine
- Not stored in the body
- Excess ingested thiamine appears in urine
- Plasma half-life of 24 hours
Dosage & Administration
- Prophylaxis: 3 to 10 mg daily
- Mild chronic deficiency: 10 to 25 mg daily
- Severe deficiency: 200 to 300 mg daily
Interaction
- No hazardous drug interactions reported
- Acts synergistically with other B-complex vitamins
- Reduced potential for adverse effects
Contraindications
- No absolute contraindications
- Risk of anaphylaxis increased by repeated parenteral administration
- Mild allergic phenomena may lead to anaphylactic shock
- Start second course of injection with lower dose
- Avoid intravenous administration except in comatose patients
- No need for parenteral administration once deficiency is corrected
Side Effects
- No adverse effects with oral administration
- Anaphylactic reactions after large intravenous doses in sensitive patients
- Increased risk with repeated parenteral administration
- Transient mild soreness at intramuscular administration site
Pregnancy & Lactation
- Safe for neonates, children, pregnant & lactating women, elderly patients
Therapeutic Class
- Vitamin-B preparations
Storage Conditions
- Protected from light and moisture