Onevit 100 mg (Tablet)
Unit Price: ৳ 0.75 (10 x 10: ৳ 75.00)
Strip Price: ৳ 7.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Thiamine hydrochloride |
| Company | Ad din pharmaceuticals ltd |
Indications
- Treatment of thiamine deficiency
- Management of Beriberi
- Wernick's encephalopathy treatment
- Neuritis associated with pregnancy
- Pellagra treatment
- Prophylactic use for low dietary intake
- Use for impaired gastrointestinal absorption of thiamine
- Increased requirements such as in pregnancy
Pharmacology
- Thiamine pyrophosphate as coenzyme
- Affects peripheral nervous system
- Affects gastrointestinal tract
- Affects cardiovascular system
- Necessary for optimal growth of infants and children
- Not stored in the body
- Rapidly lost from tissues during deficiency
- Maintenance of normal health
- Adequate daily requirement
- Symptoms of deficiency: fatigue, anorexia, tachycardia, irritability
- Causes Beriberi in alcoholics, pregnant women, malabsorption syndrome, prolonged diarrhea, hepatic disease
- Well absorbed from gastrointestinal tract
- Rapid absorption from upper small intestine
- Not stored in the body
- Excess thiamine appears in urine
- Plasma half-life of 24 hours
Dosage & Administration
- Prophylaxis: 3 to 10 mg daily
- Mild chronic deficiency: 10 to 25 mg daily
- Severe deficiency: 200 to 300 mg daily
Interaction
- No hazardous drug interactions
- Acts synergistically with other B-complex vitamins
- Reduced potential for adverse effects
Contraindications
- No absolute contraindications
- Increased risk of anaphylaxis from repeated parenteral administration
- Mild allergic phenomena as warning signs
- Avoid intravenous administration except in comatose patients
- No need for parenteral administration once deficiency is corrected
Side Effects
- No adverse effects when given orally
- Anaphylactic reactions with large intravenous doses
- Increased risk with repeated parenteral administration
- Transient mild soreness at intramuscular administration site
Pregnancy & Lactation
- Safe for neonates, children, pregnant women, lactating women, elderly patients
Therapeutic Class
- Vitamin-B preparations
Storage Conditions
- Protected from light and moisture