T-H 100 mg (Tablet)
Unit Price: ৳ 0.70 (100's pack: ৳ 70.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Thiamine hydrochloride |
| Company | Bristol pharmaceuticals ltd |
Indications
- Treatment of thiamine deficiency manifestations
- Prophylactic use in low dietary intake conditions
- Prophylactic use in impaired gastrointestinal absorption conditions
- Prophylactic use in pregnancy
- Prophylactic use in carbohydrate rich diet
Pharmacology
- Coenzyme for decarboxylation of α-ketoglutaric acid
- Affects peripheral nervous system
- Affects gastrointestinal tract
- Affects cardiovascular system
- Necessary for optimal growth of infants and children
- Not stored in the body
- Rapidly lost from tissues during deficiency
- Well absorbed from gastrointestinal tract
- Widely distributed throughout the body
- Rapid absorption from upper small intestine
- Not stored in the body
- Excess ingested thiamine appears in urine
- Plasma half life of 24 hours
Dosage & Administration
- Prophylaxis: 3 to 10 mg daily
- Mild chronic deficiency: 10 to 25 mg daily
- Severe deficiency: 200 to 300 mg daily
Interaction
- No hazardous drug interactions reported
- Acts synergistically with other B-complex vitamins
- Reduced potential for adverse effects
Contraindications
- No absolute contraindications
- Risk of anaphylaxis with repeated parenteral administration
- Mild allergic phenomena as warning signs
- Avoid intravenous administration except in comatose patients
- No need for parenteral administration after correction of deficiency
Side Effects
- No adverse effects when given orally
- Anaphylactic reactions with large intravenous doses
- Risk of reactions increases with repeated parenteral administration
- Transient mild soreness at the site of intramuscular administration
Pregnancy & Lactation
- Safe for neonates, children, pregnant and lactating women, and elderly patients
Therapeutic Class
- Vitamin-B preparations
Storage Conditions
- Protect from light and moisture